2-(Chloromethyl)-4-methylquinazoline
- CAS No.109113-72-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-(Chloromethyl)-4-methylquinazoline (CAS 109113-72-6) designed for pharmaceutical synthesis. Ideal intermediate for Linagliptin production with ≥99.0% assay.
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Product Overview
2-(Chloromethyl)-4-methylquinazoline is a specialized organic compound characterized by its quinazoline heterocyclic structure. This chemical serves as a vital building block in the pharmaceutical industry, specifically designed for complex organic synthesis pathways. Our manufacturing process ensures that each batch meets rigorous international standards for purity and consistency. As a key intermediate, it plays a crucial role in the construction of advanced therapeutic molecules, providing the necessary structural framework for subsequent chemical transformations.
The compound is engineered to facilitate efficient reaction kinetics during synthesis. Its chemical stability and reactivity profile make it a preferred choice for research and development teams focused on creating novel pharmaceutical agents. We prioritize quality control at every stage of production, from raw material sourcing to final packaging, ensuring that clients receive a product that supports their specific synthesis requirements without compromising on safety or performance.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-(Chloromethyl)-4-methylquinazoline |
| CAS Number | 109113-72-6 |
| Molecular Formula | C10H9ClN2 |
| Molecular Weight | 192.65 g/mol |
| Appearance | Light yellow powder |
| Purity | ≥99.0% |
| Melting Point | 61-63°C |
| Boiling Point | 240.04°C |
| Density | 1.251 g/cm³ |
| Flash Point | 122.14°C |
Industrial Applications
This quinazoline derivative is primarily utilized as a critical intermediate in the synthesis of Linagliptin, a prominent pharmaceutical agent used in the management of metabolic conditions. The high purity level of our product ensures minimal impurity carryover into downstream processes, which is essential for maintaining the quality of the final active pharmaceutical ingredient (API). Beyond this specific application, the compound serves as a versatile reagent in heterocyclic chemistry, enabling the development of various nitrogen-containing structures.
Chemists and process engineers value this material for its reliable performance in nucleophilic substitution reactions. The chloromethyl group provides a reactive site that allows for the efficient introduction of various functional groups, facilitating the construction of complex molecular architectures. Our supply chain is optimized to support both pilot-scale research and large-scale commercial manufacturing, ensuring continuity for long-term projects.
Quality Assurance and Safety
We adhere to strict quality management systems to guarantee product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) that verifies compliance with specified parameters. Our laboratory employs advanced analytical techniques, including HPLC and NMR, to confirm identity and purity levels. This commitment to transparency allows our partners to validate materials quickly and proceed with their synthesis workflows confidently.
- Consistent batch-to-batch reproducibility
- Comprehensive documentation and regulatory support
- Secure packaging to prevent moisture absorption
- Global logistics capabilities for timely delivery
Regarding safety and storage, the product should be kept in a cool, ventilated environment away from incompatible substances. Proper handling procedures, including the use of personal protective equipment, are recommended during laboratory operations. We provide detailed safety data sheets (SDS) upon request to ensure compliance with local occupational health and safety regulations. Our team is available to provide technical support regarding storage conditions and transportation requirements classified under UN3261.
