2-(1,3-Dioxoisoindol-2-yl)acetaldehyde
- CAS No.2913-97-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-(1,3-dioxoisoindol-2-yl)acetaldehyde (CAS 2913-97-5) is a critical pharmaceutical intermediate used primarily in the synthesis of Rucaparib. Available in bulk with strict quality control.
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Product Overview
2-(1,3-Dioxoisoindol-2-yl)acetaldehyde, identified by CAS number 2913-97-5, is a specialized organic compound serving as a vital building block in modern medicinal chemistry. This phthalimido-substituted aldehyde is extensively utilized in the pharmaceutical industry, particularly as a key intermediate in the synthesis of poly ADP-ribose polymerase (PARP) inhibitors such as Rucaparib. Our manufacturing process ensures high chemical integrity and consistency, making it an ideal choice for research and development teams focused on oncology therapeutics.
The molecular structure combines a reactive aldehyde group with a stable phthalimide moiety, offering unique reactivity profiles suitable for complex organic synthesis routes. We prioritize purity and stability in every batch, adhering to strict international standards for pharmaceutical intermediates. This product is supplied exclusively for industrial and research purposes, supporting the development of advanced therapeutic agents.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-(1,3-Dioxoisoindol-2-yl)acetaldehyde |
| CAS Number | 2913-97-5 |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.167 g/mol |
| Appearance | White powder |
| Assay | ≥98.0% |
| Melting Point | 116-118 °C |
| Boiling Point | 324.3±25.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 151.5±15.5 °C |
Industrial Applications
The primary application of this chemical lies in the synthesis of high-value pharmaceutical compounds. Specifically, it acts as a precursor in the manufacturing pipeline for Rucaparib, a targeted therapy used in the treatment of certain types of ovarian cancer. The reliability of the intermediate directly impacts the yield and purity of the final active pharmaceutical ingredient (API). Therefore, sourcing from a verified manufacturer with robust quality assurance protocols is essential.
Beyond oncology, this aldehyde derivative finds utility in various organic synthesis projects requiring the introduction of a protected amino acid equivalent or a specific heterocyclic framework. Researchers value this compound for its predictable reactivity and compatibility with standard coupling reactions. It is suitable for use in process chemistry, scale-up operations, and custom synthesis projects within regulated environments.
Quality Assurance and Packaging
Quality control is paramount in our production facility. Each batch of 2-(1,3-dioxoisoindol-2-yl)acetaldehyde undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to confirm identity and purity levels. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all relevant physical and chemical parameters to ensure compliance with your internal specifications.
Standard packaging consists of 25 kg drums, designed to protect the material from moisture and light during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements. Storage recommendations include keeping the container tightly closed in a cool, ventilated place away from incompatible substances. Proper handling ensures the longevity and stability of the product throughout its shelf life. Contact our sales team for bulk pricing, technical data sheets, and global shipping options.
