2,2,2-Trifluoroethanol
- CAS No.75-89-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,2,2-Trifluoroethanol (CAS 75-89-8) serving as a critical fluorinated solvent and intermediate for pesticide and pharmaceutical synthesis.
Request Bulk PricingProduct Technical Details
Product Overview
2,2,2-Trifluoroethanol (TFE) is a vital fluorinated organic compound widely recognized for its unique solvent properties and reactivity in chemical synthesis. As a key building block in the fine chemicals industry, this colorless transparent liquid offers exceptional stability and solvency for a variety of complex organic transformations. Our manufacturing process ensures high purity levels, making it an ideal choice for demanding applications in agrochemical and pharmaceutical production lines.
The introduction of the trifluoromethyl group significantly alters the physicochemical properties of molecules, enhancing metabolic stability and lipophilicity. Consequently, 2,2,2-Trifluoroethanol serves as an essential precursor in the development of advanced materials and therapeutic agents. We adhere to strict quality control standards to guarantee consistency across all batches, supporting large-scale industrial operations globally.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 75-89-8 |
| Molecular Formula | C2H3F3O |
| Molecular Weight | 100.040 |
| Appearance | Colorless transparent liquid |
| Assay (Purity) | ≥99.5% |
| Water Content | ≤0.1% |
| Boiling Point | 77-80 °C |
| Density | 1.393 g/cm³ |
| Refractive Index | 1.2907 |
| pH Value | 5-7 |
Industrial Applications
This fluorinated alcohol is extensively utilized as a versatile intermediate in the synthesis of high-value chemicals. In the agrochemical sector, it is a critical component for producing herbicides such as Triflusulfuron-methyl, contributing to effective crop protection solutions. Its role as a solvent and reagent facilitates efficient reaction pathways, improving yield and selectivity in multi-step synthesis processes.
In the pharmaceutical industry, 2,2,2-Trifluoroethanol is employed in the preparation of various therapeutic intermediates. It supports the synthesis of specific anesthetic agents and central nervous system modulators. Additionally, it is used in the development of proton pump inhibitors and antiarrhythmic compounds. The compound's ability to act as a trifluoroethylating agent makes it indispensable for introducing fluorine atoms into complex molecular structures, enhancing drug efficacy and pharmacokinetic profiles.
- Primary intermediate for herbicide synthesis
- Solvent for pharmaceutical organic synthesis
- Reagent for trifluoroethoxylation reactions
- Building block for fluorinated polymers
Safety and Storage
2,2,2-Trifluoroethanol is a flammable liquid with wide explosion limits and requires careful handling. It is moisture-sensitive and incompatible with strong oxidizing agents, strong acids, and active metals such as sodium or potassium. Personnel must use appropriate personal protective equipment, including gloves and eye protection, during handling operations.
For optimal stability, store the product in a cool, dry, and well-ventilated area. Keep containers tightly closed when not in use to prevent moisture absorption and contamination. Our packaging options include 25kg drums, with custom configurations available to meet specific logistical requirements. We provide comprehensive Certificates of Analysis (COA) and safety data sheets with every shipment to ensure compliance with international transport regulations.
