Intermediates

2,2,2-Trifluoroethyl Trifluoromethanesulfonate

  • CAS No.6226-25-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,2,2-trifluoroethyl trifluoromethanesulfonate (CAS 6226-25-1), a versatile fluorinated electrophilic reagent for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

2,2,2-Trifluoroethyl trifluoromethanesulfonate (CAS 6226-25-1) is a highly reactive fluorinated alkylating agent widely employed in advanced organic synthesis. As a key electrophilic trifluoroethylating reagent, it facilitates the introduction of the -CH2CF3 moiety into complex molecular architectures under mild conditions. Its exceptional reactivity and selectivity make it indispensable in the development of novel fluorinated building blocks for pharmaceutical research, agrochemical innovation, and functional materials science.

Specifications

Molecular FormulaC3H2F6O3S
Molecular Weight232.10 g/mol
AppearanceColorless liquid
Density1.61 g/cm³
Boiling Point89–91°C
Flash Point16°C
Refractive Index1.3037

Industrial Applications

This compound serves as a critical intermediate in multi-step syntheses requiring precise fluorine incorporation. Key application areas include:

  • Pharmaceutical R&D: Enables efficient construction of trifluoroethyl-containing drug candidates with enhanced metabolic stability and bioavailability.
  • Agrochemical Development: Used to synthesize next-generation pesticides and herbicides with improved environmental profiles.
  • Advanced Materials: Contributes to the production of fluorinated polymers and specialty chemicals with unique thermal and chemical resistance properties.

Manufactured under stringent quality control protocols, our product meets high industrial purity standards and is supported by comprehensive analytical documentation including Certificate of Analysis (COA). As part of a vertically integrated fluorochemical platform, we ensure reliable supply, consistent batch-to-batch performance, and technical support for scale-up processes worldwide.