2,2,3,3-Tetrafluoro-1-propanol
- CAS No.76-37-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,2,3,3-tetrafluoro-1-propanol (CAS 76-37-9), a versatile fluorinated intermediate for pharmaceutical R&D, advanced materials, and agrochemical synthesis.
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Product Overview
2,2,3,3-Tetrafluoro-1-propanol is a colorless, fluorinated aliphatic alcohol widely employed as a specialty intermediate in the synthesis of high-performance materials, active pharmaceutical ingredients (APIs), and novel agrochemical compounds. Its unique combination of strong electron-withdrawing fluorine atoms and a reactive hydroxyl group imparts distinctive solubility, stability, and reactivity profiles, making it invaluable in modern organic and medicinal chemistry workflows.
Specifications
| Molecular Formula | C₃H₄F₄O |
|---|---|
| Molecular Weight | 132.06 g/mol |
| Appearance | Colorless liquid |
| Density | 1.48 g/mL at 20 °C |
| Boiling Point | 109 °C |
| Melting Point | -15 °C |
| Flash Point | 110 °F (43.3 °C) |
| Refractive Index | n²⁰/D 1.321 |
| Storage Conditions | Store in a flammables area, away from heat, sparks, and open flames. |
| Stability | Stable under recommended conditions. Incompatible with strong oxidizing agents, strong bases, alkali metals (e.g., sodium, potassium), acid chlorides, and acid anhydrides. |
Industrial Applications
This fluorinated building block serves critical roles across multiple high-tech sectors:
- In pharmaceutical research, it acts as a key synthon for introducing trifluoromethyl-like motifs that enhance metabolic stability and membrane permeability of drug candidates.
- In advanced materials development, it contributes to the formulation of fluoropolymers, liquid crystals, and electrolytes with improved thermal and chemical resistance.
- In agrochemical innovation, it enables the construction of novel pesticide scaffolds with enhanced environmental persistence and target specificity.
As part of a comprehensive fluorochemical platform, this intermediate supports scalable, reliable manufacturing processes backed by stringent quality control and technical expertise.
