Intermediates

2-(2-Amino-1,3-Thiazol-4-Yl)Acetic Acid

  • CAS No.29676-71-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-(2-Amino-1,3-Thiazol-4-Yl)Acetic Acid (CAS 29676-71-9) designed for pharmaceutical synthesis. Reliable bulk supply with comprehensive quality documentation.

Request Bulk Pricing

Product Technical Details

Product Overview

2-(2-Amino-1,3-Thiazol-4-Yl)Acetic Acid is a critical heterocyclic building block extensively utilized in the modern pharmaceutical industry. Characterized by its unique thiazole ring structure combined with an acetic acid side chain, this compound serves as a fundamental precursor in the manufacturing of advanced cephalosporin antibiotics. Our production facility adheres to strict Good Manufacturing Practices (GMP) to ensure consistent molecular integrity and high chemical purity suitable for sensitive synthetic pathways.

As a specialized chemical intermediate, this product is engineered to meet the rigorous demands of medicinal chemistry. The presence of the amino group at the second position and the carboxylic acid functionality allows for versatile derivatization, making it an indispensable tool for chemists developing beta-lactam therapeutics. We prioritize batch-to-batch consistency to support scalable production lines.

Technical Specifications

ParameterSpecification
Chemical Name2-(2-Amino-1,3-Thiazol-4-Yl)Acetic Acid
CAS Registry Number29676-71-9
Molecular FormulaC5H6N2O2S
Molecular Weight158.18 g/mol
AppearanceWhite to yellowish to brown crystalline powder
Purity (HPLC)≥98.0%
Melting PointApprox. 130°C
Density1.552 g/cm3

Applications in Pharmaceutical Synthesis

The primary industrial application of this compound lies in the synthesis of cefotiam and related generations of cephalosporin antibiotics. Its structural properties facilitate key coupling reactions necessary for constructing the active pharmaceutical ingredient (API). Beyond antibiotic production, it is also explored in various research contexts involving heterocyclic chemistry and structure-activity relationship (SAR) studies.

  • Essential intermediate for cefotiam manufacturing
  • Used in the development of broad-spectrum antibiotics
  • Supports custom synthesis projects for novel therapeutics
  • Compatible with standard organic synthesis protocols

Quality Assurance and Packaging

Quality control is paramount in our manufacturing process. Each batch undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with international standards.

Standard packaging consists of 25 kg fiber drums lined with polyethylene bags to protect against moisture and contamination. Custom packaging solutions are available upon request to suit specific logistical requirements. We recommend storing the product in a cool, ventilated area away from direct sunlight and incompatible materials to maintain stability over time.