Intermediates

2,2-Diethoxyethylamine

  • CAS No.645-36-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,2-Diethoxyethylamine (CAS 645-36-3) is a versatile liquid intermediate essential for heterocyclic synthesis. Ideal for large-scale pharmaceutical manufacturing with consistent quality.

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Product Technical Details

Product Overview

2,2-Diethoxyethylamine represents a critical class of aminoacetals utilized extensively in modern organic synthesis and pharmaceutical development. As a stable liquid intermediate, this compound offers exceptional reactivity profiles suitable for constructing complex heterocyclic frameworks. Our manufacturing process ensures high chemical purity and consistency, making it a reliable choice for research laboratories and industrial production facilities alike.

This chemical serves as a fundamental building block in the creation of various nitrogen-containing compounds. The acetal functionality provides protective group capabilities during multi-step synthesis, while the amine group facilitates nucleophilic attacks essential for bond formation. We prioritize strict quality control measures to guarantee that every batch meets rigorous international standards for pharmaceutical intermediates.

Technical Specifications

Our production facility adheres to Good Manufacturing Practices to deliver products with precise physical and chemical properties. The following table outlines the key specifications for this grade:

Parameter Specification
CAS Number 645-36-3
Molecular Formula C6H15NO2
Molecular Weight 133.19 g/mol
Appearance Clear colorless to light yellow liquid
Purity ≥98.0%
Moisture Content ≤0.25%
Density 0.916 g/mL at 25 °C
Boiling Point 162-163 °C
Refractive Index n20/D 1.417

Industrial Applications

The primary utility of 2,2-Diethoxyethylamine lies in its role as a synthetic intermediate for medicinal chemistry. It is particularly valuable in the synthesis of imidazole-containing compounds, which are prevalent in numerous therapeutic agents. Specific applications include the construction of heteroaryl-2-imidazoles and substituted pyridine derivatives.

Chemists utilize this reagent for its ability to introduce protected aminoacetaldehyde equivalents into molecular structures. This capability is crucial when developing active pharmaceutical ingredients that require precise spatial arrangement of functional groups. Furthermore, its stability under standard storage conditions allows for flexible logistics and inventory management in large-scale manufacturing environments.

Quality Assurance and Handling

We understand that consistency is paramount in chemical manufacturing. Each production lot undergoes comprehensive analytical testing, including gas chromatography and nuclear magnetic resonance spectroscopy, to verify identity and purity. A Certificate of Analysis is provided with every shipment to ensure full traceability and compliance with your internal quality protocols.

  • Packaged in 25 kg drums or according to specific customer requirements.
  • Stored in tightly closed containers to prevent moisture absorption.
  • Kept in a cool, dry, and well-ventilated area away from incompatible substances.
  • Supported by our technical team for safe handling guidelines and usage recommendations.

Partnering with us ensures access to a global supply chain capable of meeting demanding production schedules. Whether for process development or commercial scale-up, our 2,2-Diethoxyethylamine delivers the performance and reliability required for advanced chemical synthesis.