Intermediates

2,2-Difluoroethanol

  • CAS No.359-13-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,2-Difluoroethanol (CAS 359-13-7) designed for advanced organic synthesis. Reliable supply with strict quality control for global pharmaceutical and chemical industries.

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Product Technical Details

Product Overview

2,2-Difluoroethanol stands as a pivotal fluorinated intermediate within the realm of modern organic synthesis and medicinal chemistry. As a specialized fluorinated alcohol, this compound offers unique physicochemical properties that make it indispensable for the development of advanced pharmaceutical agents and agrochemical formulations. The incorporation of fluorine atoms into organic molecules often enhances metabolic stability, lipophilicity, and bioavailability, making this building block a preferred choice for research and development teams worldwide.

Our facility produces this material under stringent quality management systems to ensure consistency across batches. We understand the critical nature of supply chain reliability in the chemical industry, which is why we maintain robust inventory levels and optimized logistics networks to serve global clients efficiently. Whether used for novel drug discovery or material science applications, our 2,2-Difluoroethanol provides the foundational purity required for high-stakes synthesis.

Physicochemical Properties

Understanding the technical specifications of 2,2-Difluoroethanol is essential for process engineers and chemists designing reaction pathways. The compound exhibits a distinct density and boiling point profile that facilitates its separation and purification during multi-step synthesis. Below is a detailed summary of its key physical and chemical characteristics:

PropertyValue
CAS Number359-13-7
Molecular FormulaC2H4F2O
Molecular Weight82.049 g/mol
AppearanceColorless transparent liquid
Assay≥98.0%
Density1.2±0.1 g/cm3
Boiling Point95.5±0.0 °C at 760 mmHg
Melting Point-28°C
Flash Point0.4±23.2 °C
Vapour Pressure26.7±0.3 mmHg at 25°C
Index of Refraction1.300

Industrial Applications

The versatility of 2,2-Difluoroethanol extends across multiple high-value sectors. In the pharmaceutical industry, it serves as a crucial precursor for synthesizing fluorinated active pharmaceutical ingredients (APIs). The presence of the difluoro group can significantly alter the electronic properties of the final molecule, often leading to improved potency and reduced toxicity profiles. Additionally, this compound is utilized in the agrochemical sector for developing next-generation pesticides and herbicides that require enhanced environmental stability.

  • Pharmaceutical Intermediate: Used in the synthesis of complex therapeutic molecules.
  • Agrochemical Building Block: Essential for creating stable crop protection agents.
  • Material Science: Applied in the development of specialized polymers and coatings.
  • Research Reagent: Employed in academic and industrial laboratories for method development.

Quality Assurance and Logistics

We prioritize quality assurance through comprehensive testing protocols. Every batch of 2,2-Difluoroethanol undergoes rigorous analysis using advanced chromatography and spectroscopy methods to verify purity and identity. A Certificate of Analysis (COA) is provided with each shipment, ensuring full transparency and compliance with international standards. Our packaging solutions are designed to maintain product integrity during transit, utilizing durable drums that meet hazardous material transportation regulations.

Storage recommendations include keeping the container in a cool, ventilated place away from incompatible substances. We offer flexible packing options, including standard 200 kg drums or custom configurations based on specific customer requirements. Our commitment to safety and quality makes us a trusted partner for bulk chemical procurement. Contact our technical sales team today to discuss your specific synthesis needs and request a competitive quote for global delivery.