2,2-Difluoroethyl p-Toluenesulfonate
- CAS No.135206-84-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,2-Difluoroethyl p-toluenesulfonate (CAS 135206-84-7) for use as a fluorinated building block in pharmaceutical and agrochemical R&D.
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Product Overview
2,2-Difluoroethyl p-toluenesulfonate is a specialized fluorinated organic intermediate widely employed in modern synthetic chemistry. This compound serves as a valuable reagent for introducing the 2,2-difluoroethyl moiety into complex molecular architectures, particularly in the development of novel pharmaceutical candidates and advanced agrochemicals. Its strategic utility stems from the electron-withdrawing nature of the difluoro group, which can significantly modulate the metabolic stability, lipophilicity, and bioavailability of target molecules.
Specifications
| Molecular Formula | C9H10F2O3S |
|---|---|
| Molecular Weight | 236.24 g/mol |
| Density | 1.166 g/cm³ |
| Boiling Point | 210.6°C at 760 mmHg |
| Flash Point | 78.8°C |
Industrial Applications
As a key fluorinated sulfonate ester, this intermediate plays a critical role in nucleophilic substitution reactions, enabling the efficient incorporation of fluorinated ethyl groups under mild conditions. Primary application sectors include:
- Pharmaceutical research and development for synthesizing fluorine-containing active pharmaceutical ingredients (APIs)
- Agrochemical innovation for next-generation pesticide design
- Advanced materials science, particularly in the creation of fluorinated polymers with enhanced thermal and chemical resistance
Manufacturers leverage this compound within integrated fluorochemical platforms that ensure stringent quality control, consistent batch-to-batch performance, and compliance with international regulatory standards for industrial chemical supply.
