2,2-Dimethoxyethanamine
- CAS No.22483-09-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,2-Dimethoxyethanamine for pharmaceutical synthesis. Reliable supply for organic chemistry applications and heterocyclic building blocks.
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Product Overview
2,2-Dimethoxyethanamine represents a critical organic building block within the pharmaceutical and fine chemical industries. Characterized by its stable acetal functionality, this compound serves as a protected form of aminoacetaldehyde, allowing chemists to introduce aminoethyl groups into complex molecular structures without premature reactivity. Our manufacturing process ensures high consistency and purity, making it an ideal choice for multi-step organic synthesis where reliability is paramount. The chemical structure provides a unique balance of nucleophilicity and stability, facilitating diverse transformation pathways in modern medicinal chemistry. As a protected amine, it prevents unwanted side reactions during harsh synthetic conditions, thereby improving overall yield and reducing purification burdens in downstream processing.
Technical Specifications and Quality Assurance
Quality control is central to our production protocol. Each batch undergoes rigorous analytical testing using advanced chromatography methods such as Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC) to confirm identity and purity levels. The physical properties are consistent with literature values, ensuring predictable behavior during reaction scale-up. We maintain strict documentation for every lot, ensuring full traceability from raw materials to finished goods. This commitment to quality supports our clients in meeting their own regulatory compliance requirements. Impurity profiles are closely monitored to ensure single impurities remain below specified thresholds, guaranteeing performance in sensitive catalytic reactions.
| Parameter | Value |
|---|---|
| CAS Number | 22483-09-6 |
| Molecular Formula | C4H11NO2 |
| Molecular Weight | 105.14 g/mol |
| Purity | ≥98.5% |
| Appearance | Colorless liquid |
| Density | 0.965 g/mL at 25 °C |
| Boiling Point | 135-139 °C at 95 mm Hg |
| Refractive Index | n20/D 1.417 |
| Flash Point | 128 °F |
Industrial Applications and Synthesis
This intermediate is extensively utilized in the preparation of heterocyclic compounds. Specifically, it acts as a key precursor in the synthesis of pyrazolo[1,5-a]pyrazine derivatives, which are valuable scaffolds in medicinal chemistry research. The dimethoxy group provides orthogonal protection strategies, enabling selective transformations in advanced drug discovery pipelines. Beyond pharmaceuticals, it finds utility in agrochemical research and material science applications requiring protected amine functionalities. Its versatility makes it a preferred choice for process chemistry teams optimizing synthetic routes for active pharmaceutical ingredients. Common reactions include condensation with carbonyl compounds followed by cyclization, leveraging the acetal hydrolysis under controlled acidic conditions to reveal the reactive aldehyde equivalent in situ.
Storage, Handling, and Logistics
To maintain optimal quality, store this material in tightly closed containers within a cool, dry, and well-ventilated facility. Keep away from incompatible substances such as strong oxidizing agents and acids which may hydrolyze the acetal group prematurely. Standard laboratory safety practices should be observed during handling, including the use of appropriate personal protective equipment such as gloves and safety goggles. We offer flexible packaging options, including 25 kg drums, to suit various production scales. Our logistics network ensures timely global delivery while maintaining product integrity throughout the supply chain. Shelf life is typically twenty-four months when stored under recommended conditions, ensuring long-term value for inventory planning. Proper labeling according to GHS standards is maintained on all outgoing shipments. Customers are advised to consult the Safety Data Sheet (SDS) for comprehensive hazard information before use.
