Intermediates

2,2-Dimethoxypropane

  • CAS No.77-76-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 2,2-Dimethoxypropane (CAS 77-76-9) designed for pharmaceutical synthesis and organic protection reactions. High purity ≥99.0% with low moisture content ensures optimal reaction yields.

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Product Technical Details

Product Overview

2,2-Dimethoxypropane, also widely recognized in the chemical industry as acetone dimethyl acetal, is a versatile organic compound serving as a critical reagent in advanced synthetic chemistry. As a leading global manufacturer, we supply this high-purity intermediate specifically formulated for pharmaceutical research and industrial organic synthesis applications. Our production process adheres to strict quality control standards, ensuring consistent molecular integrity and performance across every batch.

This colorless transparent liquid is characterized by its exceptional stability and reactivity profile, making it an indispensable tool for chemists engaged in complex molecule construction. The compound functions primarily as a protecting group reagent for diols and as a dehydrating agent in various esterification and acetalization processes. By choosing our supply, partners gain access to a reliable source of material that meets rigorous international specifications for fine chemical intermediates.

Key Features & Advantages

  • Exceptional Chemical Purity: Assay levels consistently exceed 99.0%, minimizing side reactions during sensitive synthetic steps.
  • Low Moisture Content: Controlled water levels below 0.1% prevent hydrolysis issues during storage and usage.
  • Optimized Physical Properties: Precise boiling point and density specifications ensure predictable behavior in reaction vessels.
  • Flexible Packaging Solutions: Available in standard 180 kg drums or customized packaging to suit specific logistical requirements.
  • Global Compliance: Manufactured in facilities that follow strict safety and environmental guidelines for chemical production.

Technical Specifications

ParameterSpecification
CAS Number77-76-9
Molecular FormulaC5H12O2
Molecular Weight104.15 g/mol
AppearanceColorless transparent liquid
Purity (GC)≥99.0%
Water Content (K.F.)≤0.1%
Density0.847 g/cm³
Boiling Point83°C
Refractive Index1.376-1.378

Industrial Applications

In the realm of pharmaceutical intermediates, 2,2-Dimethoxypropane is predominantly utilized for the protection of hydroxyl groups. It facilitates the formation of acetonide derivatives, which are crucial steps in the synthesis of nucleosides, carbohydrates, and various active pharmaceutical ingredients (APIs). Its ability to act as a water scavenger also makes it valuable in condensation reactions where moisture sensitivity is a critical factor.

Beyond pharmaceuticals, this compound finds utility in the production of specialty polymers and fine chemicals where precise control over functional groups is required. The high industrial purity offered by our manufacturing process ensures that downstream processes remain efficient, reducing waste and improving overall yield in large-scale production environments. Researchers rely on this material for its reproducibility and consistent performance in diverse synthetic routes.

Storage & Handling

To maintain optimal quality, 2,2-Dimethoxypropane should be stored in a cool, well-ventilated area away from direct sunlight and sources of ignition. Containers must be kept tightly sealed to prevent moisture absorption and volatilization. As with all chemical intermediates, appropriate personal protective equipment should be worn during handling, and safety data sheets should be consulted prior to use. Our logistics team ensures secure packaging to maintain product integrity during global transportation.