2,3,4,5,6-Pentafluorobenzoyl Chloride
- CAS No.2251-50-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,3,4,5,6-pentafluorobenzoyl chloride (CAS 2251-50-5) for use as a key fluorochemical intermediate in pharmaceutical and agrochemical R&D.
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Product Overview
2,3,4,5,6-Pentafluorobenzoyl chloride is a high-value fluorochemical building block widely employed in the synthesis of advanced intermediates for pharmaceuticals, agrochemicals, and liquid crystal materials. With its fully fluorinated aromatic ring and reactive acyl chloride functionality, this compound serves as a versatile reagent in nucleophilic substitution and Friedel-Crafts acylation reactions, enabling the introduction of robust, electron-deficient pentafluorophenyl moieties into complex molecular architectures.
Specifications
| Molecular Formula | C₇ClF₅O |
|---|---|
| Molecular Weight | 230.52 g/mol |
| Density | 1.601 g/cm³ |
| Boiling Point | 158–159°C |
| Refractive Index | 1.453 |
| Appearance | Colorless to pale yellow transparent liquid |
| Assay | ≥99.0% |
| Moisture | ≤0.2% |
Industrial Applications
This fluoroaromatic acyl chloride is primarily utilized as a specialty intermediate in research and industrial-scale synthesis. Key application areas include:
- Pharmaceutical development: As a precursor for fluorinated active pharmaceutical ingredients (APIs) requiring enhanced metabolic stability and membrane permeability.
- Agrochemical innovation: In the construction of novel pesticide molecules where fluorine substitution improves bioactivity and environmental persistence profiles.
- Liquid crystal technology: Serving as a monomer or derivatization agent in the production of fluorinated mesogens for high-performance display materials.
Manufactured under stringent quality control protocols, our 2,3,4,5,6-pentafluorobenzoyl chloride is supplied with comprehensive analytical documentation including Certificate of Analysis (COA). Standard packaging is 200 kg per drum, with custom options available to meet specific logistical or safety requirements. Store in a cool, dry, and well-ventilated area away from moisture and incompatible substances to maintain reactivity and shelf life.
