Intermediates

2,3,4,5,6-Pentafluorobenzyl Alcohol

  • CAS No.440-60-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,3,4,5,6-pentafluorobenzyl alcohol (CAS 440-60-8), a key fluorinated intermediate for agrochemical synthesis.

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Product Technical Details

Product Overview

2,3,4,5,6-Pentafluorobenzyl alcohol is a highly fluorinated aromatic alcohol widely employed as a critical building block in the synthesis of advanced agrochemical intermediates. With its unique electron-withdrawing pentafluoro substitution pattern, this compound offers enhanced reactivity and stability in multi-step organic transformations, making it indispensable in modern crop protection chemistry.

Specifications

Molecular FormulaC₇H₃F₅O
Molecular Weight198.090 g/mol
CAS Number440-60-8
AppearanceWhite to light yellow powder
Assay≥98.0%
Melting Point37–38 °C (lit.)
Boiling Point181.0 ± 0.0 °C at 760 mmHg
Density1.6 ± 0.1 g/cm³
Flash Point87.8 ± 0.0 °C
Vapour Pressure0.6 ± 0.3 mmHg at 25 °C
Refractive Index1.439

Industrial Applications

This fluorinated benzyl alcohol serves primarily as a high-value intermediate in the production of pyrethroid insecticides, notably in the synthesis of Fenfluthrin (CAS 75867-00-4). Its perfluorinated aromatic ring imparts metabolic stability and lipophilicity to the final active ingredient, enhancing pesticidal efficacy and environmental persistence under controlled agricultural use.

Key advantages of 2,3,4,5,6-pentafluorobenzyl alcohol in industrial settings include:

  • Excellent functional group compatibility for selective derivatization
  • High thermal and chemical stability during scale-up processes
  • Consistent batch-to-batch quality suitable for GMP-aligned manufacturing
  • Facilitates streamlined synthesis routes with reduced byproduct formation

Stored in a cool, well-ventilated area away from oxidizing agents, this product is typically supplied in 25 kg drums or customized packaging to meet global regulatory and logistical requirements.