Intermediates

2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose

  • CAS No.4132-28-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose (CAS 4132-28-9) designed for pharmaceutical synthesis. Reliable supply for Miglitol intermediate production with strict quality control.

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Product Technical Details

Product Overview

2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose is a highly specialized carbohydrate derivative utilized extensively in advanced organic synthesis and pharmaceutical manufacturing. As a fully benzylated glucose analog, this compound serves as a critical protected sugar intermediate, offering exceptional stability and reactivity profiles required for complex molecular construction. Our facility produces this reagent under stringent quality management systems to ensure consistency across batches, making it an ideal choice for research laboratories and industrial scale production alike.

The chemical structure features four benzyl protecting groups attached to the hydroxyl positions of the D-glucopyranose backbone. This specific configuration prevents unwanted side reactions during glycosylation processes, allowing chemists to achieve high stereoselectivity in the formation of glycosidic bonds. The robustness of the benzyl ether linkage ensures that the molecule withstands various reaction conditions while remaining accessible for subsequent deprotection steps when required.

Key Specifications

We adhere to rigorous analytical standards to guarantee the performance of our chemicals. Each batch undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and other validated methods to confirm identity and purity. The following table outlines the typical physical and chemical properties observed in our production runs:

ParameterSpecification
CAS Number4132-28-9
Molecular FormulaC34H36O6
Molecular Weight540.65 g/mol
AppearanceWhite to Off-White Crystalline Powder
Purity (HPLC)≥98.0%
Melting Point150-154 °C
Optical Rotation+15° to +19°
Loss on Drying≤0.5%
Residue on Ignition≤0.10%

Industrial Applications

This compound is primarily employed as a key building block in the synthesis of biologically active molecules. It is notably recognized as a vital intermediate in the production of Miglitol, an alpha-glucosidase inhibitor used in the management of diabetes. Beyond this specific application, the molecule finds utility in the development of various glycomimetics and oligosaccharide libraries. Its high purity level minimizes impurities that could interfere with downstream catalytic processes, thereby improving overall yield and reducing waste in multi-step synthesis routes.

  • Essential precursor for anti-diabetic pharmaceutical intermediates.
  • Used in stereoselective glycosylation reactions.
  • Supports research in carbohydrate chemistry and drug discovery.
  • Compatible with various organic synthesis pathways requiring protected sugars.

Quality Assurance and Handling

Quality is paramount in our manufacturing process. We implement full traceability from raw material sourcing to final packaging. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the specific test results for that batch. To maintain stability, the product should be stored in a cool, dry environment at approximately -20 °C, protected from light and moisture. Proper sealing is essential to prevent hydrolysis or degradation over extended storage periods.

We offer flexible packaging options, including 25kg cardboard drums, to suit both pilot-scale experiments and large-scale industrial requirements. Our logistics network ensures safe and timely global delivery, complying with all international shipping regulations for chemical substances. For technical inquiries or custom synthesis requests, our expert team is available to provide detailed support and documentation.