2-(3-Benzoylphenyl)propionitrile
- CAS No.42872-30-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-(3-Benzoylphenyl)propionitrile (CAS 42872-30-0), a key aromatic nitrile intermediate for advanced organic synthesis in pharmaceutical R&D and fine chemical manufacturing.
Request Bulk PricingProduct Technical Details
Product Overview
2-(3-Benzoylphenyl)propionitrile is a high-value aromatic nitrile compound widely employed as a critical building block in the synthesis of complex pharmaceutical active ingredients. With a molecular formula of C₁₆H₁₃NO and a molecular weight of 235.28 g/mol, this intermediate features a benzoyl group at the meta-position of the phenyl ring and a nitrile-functionalized propyl side chain, offering versatile reactivity for nucleophilic addition, hydrolysis, and cyclization reactions.
Specifications
| Molecular Formula | C₁₆H₁₃NO |
|---|---|
| Molecular Weight | 235.281 g/mol |
| Density | 1.115 g/cm³ |
| Boiling Point | 400.8°C at 760 mmHg |
| Melting Point | 47–53°C (lit.) |
| Flash Point | >230°F |
| Refractive Index | 1.579 |
Quality Assurance
Our 2-(3-Benzoylphenyl)propionitrile is manufactured under stringent quality control protocols compliant with international standards for pharmaceutical intermediates. Each batch undergoes comprehensive analytical validation to ensure consistency and reliability for demanding synthetic applications.
- Assay (HPLC): ≥99.0% (Typical: 99.7%)
- Water Content: ≤0.5% (Typical: 0.05%)
- Benzene Residue: ≤100 ppm (Typical: 18.4 ppm)
- Individual Impurity: ≤0.10%
- Total Impurities: ≤1.0% (Typical: 0.3%)
Industrial Applications
This compound serves primarily as a specialty intermediate in multi-step organic syntheses targeting neurological therapeutics and advanced organic molecules. Its structural motif enables efficient construction of heterocyclic scaffolds and chiral centers essential in modern drug discovery pipelines. Due to its high purity and consistent performance, it is particularly suited for use in GMP-compliant early-phase API development and scale-up processes.
