2,3-Di-O-para-toluoyl-D-tartaric Acid
- CAS No.32634-68-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity chiral intermediate essential for beta-lactam antibiotic synthesis. Available in bulk with full COA.
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Product Overview
2,3-Di-O-para-toluoyl-D-tartaric Acid, frequently recognized by its abbreviation D-DTTA, stands as a pivotal chiral building block within the modern pharmaceutical landscape. This sophisticated organic compound serves primarily as a resolving agent and a critical intermediate in the stereoselective synthesis of complex antibiotic structures. Our manufacturing process ensures exceptional enantiomeric excess, making it an indispensable resource for chemists focused on high-value medicinal chemistry projects. The compound is characterized by its stable crystalline structure and high optical purity, which are fundamental for downstream reaction success.
As a derivative of tartaric acid, this molecule inherits specific stereochemical properties that facilitate the separation of racemic mixtures. The introduction of para-toluoyl groups enhances its solubility profile in organic solvents while maintaining the rigidity required for effective chiral recognition. We prioritize rigorous quality control at every stage of production to guarantee consistency across batches, ensuring that your synthesis pathways remain uninterrupted and efficient.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 32634-68-7 |
| Molecular Formula | C20H18O8 |
| Molecular Weight | 386.35 g/mol |
| Purity | ≥99.0% |
| Melting Point | 169-171 °C |
| Specific Rotation | +136° to +143° (c=1, ethanol) |
| Appearance | White or off-white crystalline powder |
| Water Content | ≤0.50% |
Industrial Applications
The primary industrial application of 2,3-Di-O-para-toluoyl-D-tartaric Acid lies in the production of advanced beta-lactam antibiotics. Specifically, it acts as a key precursor in the synthesis of Carumonam Sodium, a potent therapeutic agent used in clinical settings. The high stereochemical integrity of this intermediate is crucial, as even minor deviations can significantly impact the efficacy and safety profile of the final pharmaceutical product. Beyond antibiotic synthesis, this compound is utilized in various fine chemical processes where chiral induction is required.
Pharmaceutical manufacturers rely on this material for its reliability in resolution processes. It enables the efficient separation of enantiomers, reducing waste and improving overall yield in multi-step synthesis routes. Our supply chain is optimized to support both pilot-scale research and large-scale commercial manufacturing, providing flexibility to clients regardless of their production volume requirements.
Quality Assurance And Storage
- Each batch undergoes comprehensive testing via HPLC and NMR to verify structural integrity and purity levels.
- Certificates of Analysis (COA) are provided with every shipment to ensure full regulatory compliance.
- Packaging is designed to prevent moisture absorption, utilizing sealed cardboard drums or customized containers.
- Storage recommendations include keeping the material in a cool, dry, and well-ventilated area away from strong light and heat sources.
- Shelf life is maximized when stored in tightly closed containers under recommended conditions.
We understand the critical nature of supply chain stability in the pharmaceutical industry. Therefore, we maintain robust inventory levels and offer global shipping solutions to meet urgent project timelines. Our technical support team is available to assist with formulation guidance and handling procedures, ensuring safe and effective utilization of this specialized chemical intermediate.
