Intermediates

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone

  • CAS No.84-58-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity DDQ oxidizing agent designed for efficient dehydrogenation and organic synthesis processes in pharmaceutical manufacturing.

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Product Technical Details

Product Overview

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone, commonly known as DDQ, is a highly selective and powerful oxidizing agent utilized extensively in modern organic synthesis. As a premier chemical intermediate, this compound plays a critical role in the dehydrogenation of steroids, the synthesis of complex heterocycles, and the preparation of advanced pharmaceutical intermediates. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for demanding research and industrial production environments where consistency and reliability are paramount.

This reagent is particularly valued for its ability to facilitate hydride abstraction reactions, enabling chemists to achieve high yields in the formation of aromatic systems from partially saturated precursors. Whether used in the development of cardiovascular therapeutic agents or antiviral pharmaceutical intermediates, DDQ provides a robust solution for oxidative transformations.

Technical Specifications

ParameterSpecification
CAS Number84-58-2
Molecular FormulaC8Cl2N2O2
Molecular Weight227.01 g/mol
AppearanceYellow or orange yellow crystalline powder
Purity (HPLC)≥98.0%
Melting Point214-217 °C
Loss on Drying≤0.5%
Residue on Ignition≤0.1%

Industrial Applications

The versatility of 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone extends across multiple sectors of the fine chemical and pharmaceutical industries. Its primary function as an electron transfer reagent makes it indispensable for the synthesis of quinoline derivatives via imine and alkyne coupling. Furthermore, it serves as a universal deprotection reagent for various functional groups, including thioacetals, acetals, and ketals, streamlining multi-step synthesis routes.

  • Efficient dehydrogenation reagent for steroid hormone synthesis.
  • Oxidizing agent for the production of therapeutic agents and cardiovascular medications.
  • Key component in the synthesis of 1,2-benzioxazole compounds.
  • Advanced organic synthesis for perfume and fragrance ingredients.
  • Reliable intermediate for complex pharmaceutical manufacturing processes.

Quality Assurance and Storage

Quality control is integral to our production workflow. Every batch of DDQ undergoes rigorous testing via IR spectroscopy and melting point analysis to confirm identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment to ensure compliance with international standards. To maintain stability, the product should be stored in a cool, ventilated warehouse away from fire and heat sources. The storage temperature should not exceed 37 °C. Packaging is available in 25 kg barrels, with customization options to meet specific logistical requirements. As a global manufacturer, we are committed to delivering safe, compliant, and high-performance chemical solutions to partners worldwide.