2,3-Dichloro-5-fluoropyridine
- CAS No.185985-40-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,3-Dichloro-5-fluoropyridine is a essential fluorinated heterocyclic intermediate used extensively in pharmaceutical and agrochemical synthesis.
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Product Overview
2,3-Dichloro-5-fluoropyridine is a highly valued fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern on the pyridine ring, this chemical intermediate offers versatile reactivity profiles suitable for complex molecular construction. The presence of the fluorine atom at the fifth position enhances the metabolic stability and bioavailability of downstream pharmaceutical products, making it a preferred choice for medicinal chemists developing novel therapeutic agents.
Our manufacturing facility produces this compound under strict quality control standards to ensure consistent purity and performance. As a leading global manufacturer, we understand the demanding requirements of the pharmaceutical and agrochemical industries. Therefore, every batch undergoes rigorous analytical testing to confirm identity, purity, and physical properties before release.
Chemical Properties and Specifications
The chemical structure of 2,3-Dichloro-5-fluoropyridine allows for selective nucleophilic substitution reactions, particularly at the chloro positions. This reactivity is leveraged to introduce various functional groups during multi-step synthesis pathways. The physical properties are tightly controlled to facilitate handling and processing in industrial settings.
| Parameter | Specification |
|---|---|
| CAS Number | 185985-40-4 |
| Molecular Formula | C5H2Cl2FN |
| Molecular Weight | 165.98 g/mol |
| Appearance | White Crystalline Powder |
| Purity | ≥99.0% |
| Boiling Point | 174°C at 760 mmHg |
| Density | 1.498 g/cm3 |
| Flash Point | 59.1°C |
Industrial Applications
This fluorinated pyridine derivative is primarily utilized as a key intermediate in the synthesis of pharmaceuticals, including quinolone antibiotics and kinase inhibitors. The fluorine substituent plays a crucial role in modulating the electronic properties of the final drug molecule, often improving binding affinity to biological targets. Additionally, it finds significant application in the agrochemical sector for the production of advanced herbicides and fungicides.
Chemists value this compound for its ability to participate in cross-coupling reactions and nucleophilic aromatic substitutions. Its stability under various reaction conditions makes it a reliable starting material for scaling up production from laboratory research to commercial manufacturing. We support our clients with technical data and synthesis route recommendations to optimize their production processes.
Quality Assurance and Storage
Quality is the cornerstone of our operation. We implement a comprehensive quality management system that covers raw material sourcing, production monitoring, and final product inspection. Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results against established specifications. This transparency ensures that our partners can maintain their own quality standards without interruption.
For optimal stability, 2,3-Dichloro-5-fluoropyridine should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is important to protect the material from moisture and direct sunlight to prevent degradation. Standard packaging includes 25kg drums, customized to meet specific logistical requirements. Our logistics team ensures safe and compliant global shipping, adhering to all international regulations for chemical transport.
