Intermediates

2',3'-Dideoxyguanosine

  • CAS No.85326-06-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2',3'-Dideoxyguanosine intermediate for antiviral pharmaceutical research and synthesis.

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Product Technical Details

Product Overview

2',3'-Dideoxyguanosine, frequently abbreviated as ddG, represents a significant nucleoside analogue within the realm of medicinal chemistry and pharmaceutical development. As a specialized chemical entity, this compound serves as a foundational building block for the synthesis of advanced antiviral therapeutics. Our facility produces this material under strict quality control protocols to ensure consistency and reliability for research and industrial applications.

The chemical structure features a modified sugar moiety lacking hydroxyl groups at the 2' and 3' positions, which is critical for its biological activity profile in specific enzymatic pathways. This structural modification makes it an invaluable tool for scientists engaged in the discovery and development of novel antiviral agents. We understand the critical nature of purity in pharmaceutical synthesis, which is why our manufacturing process emphasizes high-resolution purification techniques.

Technical Specifications

ParameterSpecification
Chemical Name2',3'-Dideoxyguanosine
CAS Registry Number85326-06-3
Molecular FormulaC10H13N5O3
Molecular Weight251.24 g/mol
AppearanceWhite to off-white powder
Assay (HPLC)≥98.0%
Density1.91 g/cm3
Boiling Point632.1°C
Flash Point336.1°C

Industrial Applications

This nucleoside analogue is primarily utilized as a critical intermediate in the synthesis of antiviral pharmaceuticals. It plays a pivotal role in the research and development sector, enabling chemists to explore new therapeutic avenues against viral infections. The high purity level ensures that downstream reactions proceed with minimal impurities, reducing the need for extensive purification steps in later stages of drug manufacturing.

Beyond direct synthesis, 2',3'-Dideoxyguanosine is employed in biochemical research to study enzyme kinetics and nucleoside metabolism. Its stability and defined chemical properties make it a reliable standard for laboratory assays. We support various scales of operation, from early-stage discovery labs to large-scale pilot production facilities.

Quality Assurance and Storage

Quality is paramount in our production process. Each batch undergoes rigorous testing using High-Performance Liquid Chromatography (HPLC) to verify assay levels and identify potential contaminants. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for that lot. This transparency allows our clients to maintain their own quality standards without compromise.

Proper storage is essential to maintain the integrity of the chemical. The product should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent degradation. Our packaging options include 25 kg drums, with flexibility to accommodate specific customer requirements for larger or smaller quantities. We ensure secure packaging to prevent damage during international transit.

Why Choose Our Supply

  • Consistent high purity levels suitable for pharmaceutical synthesis.
  • Comprehensive documentation including COA and MSDS.
  • Flexible packaging solutions tailored to client needs.
  • Reliable global shipping and logistics support.
  • Competitive bulk pricing for long-term partnerships.

Partner with us for your 2',3'-Dideoxyguanosine requirements. Our team of experts is ready to assist with technical inquiries and supply chain optimization to support your research and production goals.