Intermediates

2,3-Difluoro-4-iodobenzaldehyde

  • CAS No.885590-99-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,3-Difluoro-4-iodobenzaldehyde (CAS 885590-99-8) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

2,3-Difluoro-4-iodobenzaldehyde is a highly specialized fluorinated building block engineered for complex organic synthesis applications. As a critical intermediate in the pharmaceutical and agrochemical industries, this compound offers unique reactivity profiles due to the strategic positioning of fluorine and iodine substituents on the benzaldehyde core. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for researchers and industrial chemists seeking reliable raw materials for multi-step synthesis pathways.

The incorporation of fluorine atoms often enhances the metabolic stability and bioavailability of final drug candidates, while the iodine moiety facilitates versatile cross-coupling reactions such as Suzuki-Miyaura or Heck couplings. This dual functionality makes the compound a valuable asset in the development of novel therapeutic agents and advanced functional materials.

Key Features and Advantages

  • High Chemical Purity: Guaranteed ≥99.0% purity via GC analysis to minimize side reactions.
  • Strategic Substitution: Optimized fluorine and iodine placement for targeted synthetic routes.
  • Robust Stability: Carefully processed to maintain integrity during storage and transport.
  • Scalable Supply: Capable of meeting bulk demands for pilot plant and commercial production.
  • Comprehensive Documentation: Full COA and technical support provided with every shipment.

Technical Specifications

ParameterValue
Chemical Name2,3-Difluoro-4-iodobenzaldehyde
CAS Number885590-99-8
Molecular FormulaC7H3F2IO
Molecular Weight267.99 g/mol
AppearancePale yellow powder
Purity (GC)≥99.0%
Melting Point98-101°C
Boiling Point261.7°C
Density2.036 g/cm³
Flash Point112.1°C
Refractive Index1.614

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of pharmaceutical active ingredients (APIs), where precise halogenation is required for downstream functionalization. It serves as a key precursor in the production of kinase inhibitors, anti-inflammatory agents, and other specialized medicinal compounds. Additionally, it finds application in the agrochemical sector for developing novel pesticides and herbicides with improved environmental profiles. Material science researchers also leverage this compound for creating organic electronic materials and polymers with specific electronic properties.

Storage and Handling

To maintain optimal quality, 2,3-Difluoro-4-iodobenzaldehyde should be stored in a cool, well-ventilated area away from direct sunlight and moisture. The container must remain tightly sealed when not in use to prevent degradation. Standard laboratory safety protocols should be followed during handling, including the use of appropriate personal protective equipment. We offer flexible packaging options, including 25 kg drums, and can customize packaging solutions to meet specific logistical requirements for global distribution.