2,3-Difluoro-4-methoxybenzonitrile
- CAS No.256417-12-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 2,3-Difluoro-4-methoxybenzonitrile designed for complex organic synthesis and pharmaceutical intermediate applications.
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Product Overview
2,3-Difluoro-4-methoxybenzonitrile is a highly specialized fluorinated aromatic compound serving as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern, this molecule combines the electron-withdrawing properties of fluorine atoms with the versatility of a nitrile group and a methoxy ether. These structural features make it an invaluable precursor for the development of advanced pharmaceutical agents, agrochemicals, and functional materials. Our manufacturing process ensures consistent quality and high purity, meeting the rigorous demands of research and industrial production environments.
The strategic placement of fluorine atoms at the 2 and 3 positions enhances metabolic stability and lipophilicity in downstream drug candidates, while the 4-methoxy group offers additional sites for chemical modification. This compound is particularly sought after in medicinal chemistry programs focused on kinase inhibitors and receptor modulators, where precise structural control is paramount.
Key Specifications
We adhere to strict quality control protocols to guarantee the performance of every batch. The following table outlines the standard physical and chemical properties verified through advanced analytical techniques such as HPLC, NMR, and GC-MS.
| Parameter | Value |
|---|---|
| CAS Number | 256417-12-6 |
| Molecular Formula | C8H5F2NO |
| Molecular Weight | 169.128 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Assay (Purity) | ≥98.0% |
| Moisture Content | ≤0.5% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 240.1±35.0 °C at 760 mmHg |
| Flash Point | 99.0±25.9 °C |
Industrial Applications
As a versatile intermediate, this fluorinated nitrile finds extensive use across multiple high-value sectors. In the pharmaceutical industry, it serves as a key starting material for synthesizing complex active pharmaceutical ingredients (APIs). The nitrile functionality allows for conversion into carboxylic acids, amines, or tetrazoles, enabling diverse synthetic routes. Additionally, the fluorine substituents are crucial for optimizing the pharmacokinetic profiles of final drug products.
Beyond pharmaceuticals, this compound is utilized in the agrochemical sector for developing novel pesticides and herbicides with improved environmental profiles. Its stability and reactivity make it suitable for creating specialized polymers and liquid crystals used in electronic materials. Our global supply chain supports both large-scale manufacturing needs and smaller research quantities, ensuring flexibility for our partners.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Each production batch undergoes comprehensive testing to verify identity, purity, and impurity profiles. We provide a Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our facility operates under standardized management systems to ensure traceability and compliance with international trade regulations.
- Packaged in 25 kg drums or according to specific customer requirements.
- Stored in a cool, ventilated area away from direct sunlight and moisture.
- Protected from incompatible substances to maintain chemical integrity.
- Available for custom synthesis and scale-up projects upon request.
For technical inquiries, bulk pricing, or sample requests, our expert team is ready to assist you in optimizing your synthesis pathways with our high-performance chemical intermediates.
