2,3-Difluoro-5-chloropyridine

Product Overview

2,3-Difluoro-5-chloropyridine is a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. Recognized by its CAS registry number 89402-43-7, this chemical intermediate is prized for its unique reactivity profile, which enables the efficient construction of complex molecular architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for large-scale industrial applications ranging from agrochemical development to pharmaceutical research.

The presence of both fluorine and chlorine substituents on the pyridine ring enhances the compound's lipophilicity and metabolic stability, properties that are highly sought after in the design of advanced active ingredients. As a leading global manufacturer, we prioritize strict quality control measures to deliver materials that meet the rigorous demands of synthetic chemistry laboratories and production facilities worldwide. This commitment to excellence ensures that every drum shipped meets the highest standards of purity and performance.

Key Physical and Chemical Properties

Understanding the physical characteristics of 2,3-Difluoro-5-chloropyridine is essential for safe handling and optimal reaction outcomes. The substance typically presents as a colorless to pale yellow liquid, indicating high purity levels when properly stored. Its specific density and boiling point facilitate straightforward integration into various synthesis routes without requiring extreme processing conditions. Proper knowledge of these parameters allows chemists to design safer and more efficient reaction protocols.

• High Chemical Purity: Assay levels typically exceed 98.0%, minimizing side reactions and downstream purification costs.
• Thermal Stability: Suitable for processes requiring moderate heating up to specified boiling points without degradation.
• Low Moisture Content: Controlled at ≤0.5% to prevent hydrolysis during sensitive nucleophilic substitution reactions.
• Refractive Index: Consistent optical properties ensure rapid identity verification during quality control checks.

Industrial Applications

This fluorinated pyridine derivative is predominantly utilized as a key intermediate in the synthesis of agrochemicals, most notably serving as a precursor for Clodinafop Propargyl. Its role in this context underscores its importance in the production of effective herbicides that support global agricultural productivity. Additionally, the compound finds utility in pharmaceutical intermediates, where the introduction of fluorine atoms can significantly improve the bioavailability and binding affinity of drug candidates.

Researchers and process chemists value this material for its versatility in nucleophilic substitution reactions, allowing for the selective modification of the pyridine ring. Whether used in discovery chemistry or scale-up manufacturing, 2,3-Difluoro-5-chloropyridine provides a reliable foundation for developing next-generation chemical solutions. Its stability under various reaction conditions makes it a preferred choice for multi-step synthesis pathways.

Quality Specifications and Packaging

We adhere to international standards to guarantee the safety and efficacy of our chemical products. Each batch undergoes comprehensive analysis using gas chromatography and other validated methods to confirm compliance with factory standards. The table below outlines the typical specification profile for our standard grade material, ensuring transparency for our partners.

For further technical details or to request a Certificate of Analysis (COA), please contact our sales team. We offer flexible packaging options to suit specific logistical requirements and ensure safe global delivery. Our dedicated support staff is available to assist with technical inquiries regarding storage conditions and compatibility with other reagents.