Intermediates

2,3-Difluoro-6-methylpyridine

  • CAS No.1227579-04-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,3-Difluoro-6-methylpyridine liquid for pharmaceutical synthesis. Available in bulk with COA.

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Product Technical Details

Product Overview

2,3-Difluoro-6-methylpyridine is a highly specialized fluorinated heterocyclic compound designed for advanced organic synthesis and medicinal chemistry applications. As a key building block in the pharmaceutical industry, this compound features a unique substitution pattern that enhances the metabolic stability and lipophilicity of final drug candidates. Our manufacturing process ensures exceptional consistency, making it an ideal choice for researchers and production facilities focused on developing novel therapeutic agents.

We understand the critical nature of supply chain reliability in the chemical sector. Therefore, every batch of 2,3-Difluoro-6-methylpyridine undergoes rigorous quality control testing using state-of-the-art analytical instrumentation. This commitment to excellence guarantees that our clients receive materials that meet the strictest international standards for purity and performance.

Technical Specifications

ParameterValue
Chemical Name2,3-Difluoro-6-methylpyridine
CAS Number1227579-04-5
Molecular FormulaC6H5F2N
Molecular Weight129.11 g/mol
AppearanceColorless to Pale Yellow Liquid
Purity≥99.0% (GC)
Packing25kg/Drum

Applications in Pharmaceutical Synthesis

Fluorinated pyridines are indispensable in modern drug discovery due to the unique electronic and steric properties imparted by fluorine atoms. 2,3-Difluoro-6-methylpyridine serves as a versatile intermediate for constructing complex molecular architectures. It is frequently utilized in the synthesis of kinase inhibitors, receptor modulators, and other biologically active small molecules. The presence of fluorine substituents at the 2 and 3 positions allows for selective functionalization, enabling chemists to introduce diverse side chains with high precision.

  • Used as a core scaffold for developing central nervous system therapeutics.
  • Employed in the synthesis of anti-inflammatory and antiviral agents.
  • Facilitates cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig.
  • Enhances bioavailability and membrane permeability in final API structures.

Quality Assurance and Storage

Quality is the cornerstone of our operation. We implement a comprehensive quality management system that covers every stage from raw material sourcing to final product dispatch. Each shipment is accompanied by a Certificate of Analysis (COA) detailing specific test results including purity, identity, and residual solvents. This transparency allows our partners to validate materials quickly and proceed with their synthesis workflows without delay.

Proper storage is essential to maintain the integrity of fluorinated intermediates. 2,3-Difluoro-6-methylpyridine should be stored in a tightly closed container in a cool, dry, and well-ventilated area. It is recommended to keep the material away from strong oxidizing agents and moisture to prevent degradation. For long-term storage, maintaining an inert atmosphere such as nitrogen or argon is advisable. Our packaging solutions are designed to protect the product during global transit, ensuring it arrives in optimal condition regardless of destination.

As a global manufacturer, we are committed to supporting our clients with technical expertise and reliable logistics. Whether you require sample quantities for research or bulk volumes for commercial production, our team is equipped to meet your demands efficiently. Contact us today to discuss your specific requirements and request a competitive quote for 2,3-Difluoro-6-methylpyridine.