2,3-Difluoro-6-nitroaniline
- CAS No.211693-73-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,3-Difluoro-6-nitroaniline intermediate for pharmaceutical synthesis. ≥99.0% purity, global supply, and comprehensive COA documentation available.
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Product Overview
Welcome to our detailed specification sheet for 2,3-Difluoro-6-nitroaniline, a premium fluorinated aromatic intermediate engineered for advanced pharmaceutical and organic synthesis applications. This compound serves as a critical building block in the development of complex medicinal agents, leveraging the unique metabolic stability and lipophilicity provided by fluorine substitution. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial production environments.
As a specialized chemical supplier, we understand the rigorous requirements of modern drug discovery. This nitroaniline derivative offers excellent reactivity for further functionalization, making it an indispensable tool for chemists working on novel therapeutic pathways. The strategic placement of fluoro groups enhances the biological profile of downstream molecules, aligning with current trends in medicinal chemistry.
Key Features and Advantages
- Exceptional Chemical Purity: Manufactured to meet or exceed 99.0% purity standards, minimizing impurities that could affect downstream reactions.
- Enhanced Reactivity: The nitro and amino groups provide versatile sites for reduction, substitution, and coupling reactions.
- Fluorine Benefits: Incorporation of fluorine atoms improves metabolic stability and membrane permeability in final pharmaceutical products.
- Reliable Supply Chain: Supported by robust production capacity and global logistics to ensure timely delivery for large-scale projects.
- Quality Assurance: Every batch is accompanied by a comprehensive Certificate of Analysis (COA) and technical support documentation.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2,3-Difluoro-6-nitroaniline |
| CAS Number | 211693-73-1 |
| Molecular Formula | C6H4F2N2O2 |
| Molecular Weight | 174.11 g/mol |
| Appearance | Off-white to Light Yellow Powder |
| Purity | ≥99.0% (HPLC) |
| Density | 1.554 g/cm3 |
| Boiling Point | 284.2ºC at 760 mmHg |
| Flash Point | 125.7ºC |
| Refractive Index | 1.495 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the pharmaceutical industry as a precursor for synthesizing active pharmaceutical ingredients (APIs). Its structure allows for diverse chemical transformations, including nucleophilic aromatic substitution and reduction of the nitro group to form diamines. Researchers value this compound for its role in creating kinase inhibitors, antibacterial agents, and other specialized therapeutics where fluorine substitution is critical for efficacy.
Beyond pharmaceuticals, this chemical finds utility in agrochemical research and material science, where specific electronic properties are required. Our team provides technical consultation to help integrate this intermediate into your specific synthesis routes efficiently. We support scale-up from laboratory grams to industrial tonnage, ensuring process consistency throughout your development lifecycle.
Storage and Handling
To maintain optimal quality, 2,3-Difluoro-6-nitroaniline should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is essential to keep the material away from incompatible substances such as strong oxidizing agents and acids. Proper personal protective equipment (PPE), including gloves and safety goggles, should be worn during handling to prevent skin contact or inhalation of dust. Adherence to standard laboratory safety protocols ensures a secure working environment.
For bulk orders, custom packaging solutions are available upon request. We recommend consulting our safety data sheet (SDS) for detailed hazard information and emergency measures. Our commitment to safety and quality makes us a trusted partner for your chemical sourcing needs.
