2,3-Difluorophenylacetonitrile
- CAS No.145689-34-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity liquid intermediate for advanced organic synthesis. Ideal for pharmaceutical and agrochemical manufacturing processes.
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Product Overview
2,3-Difluorophenylacetonitrile is a specialized fluorinated organic compound designed for high-performance chemical synthesis. As a critical building block in modern medicinal chemistry and agrochemical development, this nitrile derivative offers exceptional reactivity and stability. The introduction of fluorine atoms at the 2 and 3 positions of the phenyl ring significantly enhances the metabolic stability and lipophilicity of downstream molecules, making it a preferred choice for research and industrial applications.
Our manufacturing process adheres to strict quality control standards to ensure consistent batch-to-batch reliability. We understand that precision in molecular structure is paramount for complex synthesis routes. Therefore, each production run undergoes rigorous analytical testing to verify purity levels and physical properties. This commitment to excellence allows our partners to streamline their development timelines and reduce purification burdens during subsequent reaction steps.
Technical Specifications
The following table outlines the key physical and chemical properties of our premium grade 2,3-Difluorophenylacetonitrile. These parameters are verified using advanced spectroscopic and chromatographic methods.
| Parameter | Value |
|---|---|
| CAS Number | 145689-34-5 |
| Molecular Formula | C8H5F2N |
| Molecular Weight | 153.129 g/mol |
| Appearance | Clear, very pale lemon/lime liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 216.9±25.0 °C at 760 mmHg |
| Melting Point | 24ºC |
| Flash Point | 85.0±23.2 °C |
| Refractive Index | 1.487 |
Industrial Applications
This fluorinated intermediate serves as a versatile precursor in the synthesis of various high-value compounds. In the pharmaceutical sector, it is utilized to construct complex heterocyclic systems found in novel therapeutic agents. The electron-withdrawing nature of the fluorine substituents facilitates specific nucleophilic substitutions and cyclization reactions that are difficult to achieve with non-fluorinated analogs.
Additionally, the agrochemical industry leverages this compound for the development of advanced crop protection solutions. Its structural features contribute to the biological activity and environmental profile of final products. Whether used in custom synthesis projects or large-scale manufacturing, 2,3-Difluorophenylacetonitrile provides a reliable foundation for innovation. Our technical team is available to assist with formulation guidance and process optimization to maximize yield and efficiency.
Storage and Handling
To maintain optimal quality, this product should be stored in a cool, ventilated place away from direct sunlight and heat sources. Containers must be kept tightly closed when not in use to prevent moisture absorption or contamination. We recommend following standard safety protocols for handling organic nitriles, including the use of appropriate personal protective equipment. Our packaging options include 200 kg drums, with custom configurations available to meet specific logistical requirements. Global shipping services ensure timely delivery while maintaining product integrity throughout the supply chain.
