2,3-Difluoropyridine
- CAS No.1513-66-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,3-Difluoropyridine (CAS 1513-66-2) available for pharmaceutical synthesis. Reliable supply for research and industrial scale production.
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Product Overview
2,3-Difluoropyridine is a highly valued fluorinated heterocyclic compound widely utilized in the pharmaceutical and agrochemical industries. As a critical building block, this substance serves as a foundational element for constructing complex molecular architectures required in modern drug discovery. Our facility specializes in the production of this intermediate with stringent quality controls to ensure consistency across batches. The introduction of fluorine atoms into the pyridine ring significantly enhances metabolic stability and bioavailability, making it an essential component for developing next-generation therapeutics.
We understand the demanding requirements of medicinal chemistry and process research. Therefore, our manufacturing processes are designed to deliver superior purity levels suitable for multi-step synthesis routes. Whether used in early-stage research or scaled-up commercial production, our 2,3-Difluoropyridine provides the reliability needed to maintain project timelines and regulatory compliance.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2,3-Difluoropyridine |
| CAS Number | 1513-66-2 |
| Molecular Formula | C5H3F2N |
| Molecular Weight | 115.08 g/mol |
| Appearance | Yellow liquid |
| Purity | ≥99.0% |
| Boiling Point | 116.5±20.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Refractive Index | 1.447 |
| Packing | 25kg/drum |
Pharmaceutical Applications
This fluorinated pyridine derivative plays a pivotal role in the synthesis of advanced pharmaceutical agents. It is frequently employed in the preparation of specialized derivatives such as 2,7-diazaspiro compounds which act as enzyme inhibitors. Specifically, it contributes to the development of candidates targeting 11-beta hydroxysteroid dehydrogenase type 1 and mineralocorticoid receptor antagonists. These therapeutic areas are critical for managing metabolic disorders and cardiovascular conditions.
The unique reactivity of the 2,3-difluoro substitution pattern allows for selective nucleophilic aromatic substitution reactions. This chemical behavior enables chemists to introduce diverse functional groups at specific positions on the ring system. Such versatility is indispensable when optimizing lead compounds for potency and selectivity. Our product supports the creation of novel chemical entities that meet the rigorous standards of global regulatory bodies.
Quality and Safety Assurance
Safety and quality are paramount in our operations. Each batch of 2,3-Difluoropyridine undergoes comprehensive analytical testing including GC, HPLC, and NMR spectroscopy to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability. Regarding handling, this material should be stored in a tightly closed container within a cool and dry environment. It is crucial to avoid exposure to oxidizing agents to maintain stability.
Our packaging ensures secure transport via 25kg drums, minimizing the risk of contamination or leakage. We adhere to international shipping regulations for chemical substances, ensuring that your supply chain remains uninterrupted. Our technical team is available to provide guidance on safe handling procedures and storage conditions tailored to your facility requirements.
Why Choose Our Facility
- Consistent high purity levels exceeding 99 percent for reliable synthesis outcomes.
- Scalable production capacity to support both research and commercial manufacturing needs.
- Comprehensive documentation including COA and MSDS for regulatory compliance.
- Competitive bulk pricing structures for long-term partnership agreements.
- Global logistics network ensuring timely delivery to major pharmaceutical hubs.
Selecting the right supplier for critical intermediates is a strategic decision. We commit to delivering not just a chemical product but a partnership grounded in quality and reliability. Contact our sales team today to discuss your specific requirements and request a sample for evaluation.
