Intermediates

2,3-Dihydrobenzofuran

  • CAS No.496-16-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,3-Dihydrobenzofuran (CAS 496-16-2) supplied for pharmaceutical synthesis. Ideal intermediate for Darifenacin production with strict quality control.

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Product Technical Details

Product Overview

2,3-Dihydrobenzofuran is a premier heterocyclic organic compound widely recognized for its critical role in modern medicinal chemistry and pharmaceutical manufacturing. As a specialized building block, this chemical serves as an essential precursor in the synthesis of complex therapeutic agents. Our facility produces this compound under rigorous quality management systems to ensure consistency and reliability for downstream applications. The molecule features a saturated furan ring fused to a benzene ring, providing unique reactivity profiles that are highly valued in organic synthesis pathways.

We understand the demands of the global pharmaceutical supply chain. Therefore, our production processes are optimized to deliver high purity levels suitable for sensitive reaction sequences. Whether used in research and development or scaled for industrial manufacturing, this intermediate provides the foundational chemistry required for creating advanced neurological therapeutics and other specialized medications.

Technical Specifications

Quality and precision are paramount in chemical manufacturing. Below are the detailed physical and chemical properties verified through our internal quality control laboratories. Each batch is tested to confirm compliance with international standards.

ParameterSpecification
CAS Number496-16-2
Molecular FormulaC8H8O
Molecular Weight120.148 g/mol
AppearanceColorless to light yellow transparent liquid
Assay (Purity)≥98.0%
Density1.1±0.1 g/cm3
Boiling Point188.2±10.0 °C at 760 mmHg
Melting Point-21°C
Flash Point66.7±0.0 °C
Refractive Index1.560

Industrial Applications

The primary utility of 2,3-Dihydrobenzofuran lies in its function as a key intermediate for the synthesis of active pharmaceutical ingredients (APIs). Notably, it is utilized in the production pathway of Darifenacin and its hydrobromide salt, which are significant compounds in the management of overactive bladder conditions. The structural integrity of this benzofuran derivative allows for specific functionalization reactions required to construct the final drug molecule.

Beyond specific API synthesis, this chemical is valuable for researchers developing new heterocyclic libraries. Its stability and reactivity make it a suitable candidate for various coupling reactions and structural modifications. Pharmaceutical companies and contract research organizations rely on consistent supply chains for such intermediates to maintain their production schedules and regulatory compliance.

Quality Assurance and Storage

Every shipment of 2,3-Dihydrobenzofuran is accompanied by a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Our quality assurance team conducts multiple checkpoints during production to verify purity, identity, and physical properties. We employ advanced chromatographic techniques to ensure the assay meets or exceeds the 98.0% threshold.

For optimal preservation, the product should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. Standard packaging includes 200 kg drums, though we offer flexible packaging solutions tailored to customer requirements. Our logistics network ensures safe global delivery, maintaining the chemical's stability throughout transit. Partner with us for reliable supply, competitive bulk pricing, and technical support for your synthesis needs.