2,4,5-Trifluorobenzoic Acid
- CAS No.446-17-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,4,5-Trifluorobenzoic Acid (CAS 446-17-3) designed for pharmaceutical synthesis and liquid crystal material manufacturing.
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Product Overview
2,4,5-Trifluorobenzoic Acid is a highly specialized fluorinated aromatic compound that serves as a essential building block in modern organic synthesis. As a key intermediate, this chemical structure incorporates three fluorine atoms at specific positions on the benzene ring, significantly altering its electronic properties and reactivity compared to non-fluorinated analogs. Our facility produces this compound under strict quality control standards to ensure consistency for downstream applications in medicinal chemistry and advanced material science.
The strategic placement of fluorine substituents enhances the metabolic stability and lipophilicity of molecules derived from this acid. This makes it an invaluable precursor for researchers and industrial manufacturers aiming to develop novel therapeutic agents or high-performance electronic materials. We commit to providing a reliable supply chain for this critical chemical entity.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 446-17-3 |
| Molecular Formula | C7H3F3O2 |
| Molecular Weight | 176.09 g/mol |
| Appearance | White to off-white powder |
| Assay (Purity) | ≥98.0% |
| Moisture Content | ≤0.2% |
| Melting Point | 94-96°C |
| Density | 1.536 g/cm3 |
Industrial Applications
In the pharmaceutical sector, 2,4,5-Trifluorobenzoic Acid is frequently utilized in the synthesis of complex active pharmaceutical ingredients (APIs). The fluorine atoms act as bioisosteres for hydrogen or hydroxyl groups, often improving the binding affinity of drug candidates to their biological targets. Furthermore, the carbon-fluorine bond strength contributes to reduced metabolic clearance, potentially extending the half-life of therapeutic compounds. This attribute is particularly valuable in the development of treatments for chronic conditions where sustained efficacy is required.
Beyond healthcare, this compound plays a pivotal role in the production of liquid crystal materials. The unique electronic characteristics imparted by the trifluoro substitution pattern influence the dielectric anisotropy and birefringence of liquid crystal mixtures. These properties are critical for the performance of display technologies used in consumer electronics and industrial monitoring systems. Our material is processed to meet the rigorous purity demands of the electronics industry.
Quality Assurance and Packaging
We understand that consistency is paramount in chemical manufacturing. Every batch of 2,4,5-Trifluorobenzoic Acid undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to verify structural integrity and purity levels. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified parameters.
- Standard packaging includes 25 kg drums designed for safe international transport.
- Custom packaging solutions are available to meet specific client logistical requirements.
- Products are stored in cool, ventilated facilities to maintain stability prior to dispatch.
- Global shipping networks ensure timely delivery to manufacturing sites worldwide.
- Dedicated technical support is available for synthesis route optimization inquiries.
Proper storage involves keeping the container tightly closed in a dry environment away from incompatible materials. By adhering to these guidelines, users can maintain the quality of the material throughout its shelf life. Partner with us for a secure source of high-quality fluorinated intermediates.
