Intermediates

2,4,6-Trifluorophenol

  • CAS No.2268-17-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,4,6-Trifluorophenol (CAS 2268-17-9) designed for advanced organic synthesis and pharmaceutical intermediate applications with guaranteed quality.

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Product Technical Details

Product Overview

2,4,6-Trifluorophenol represents a critical fluorinated aromatic compound utilized extensively in modern organic synthesis and medicinal chemistry. As a specialized building block, this substance offers unique reactivity profiles due to the strong electron-withdrawing effects of the three fluorine substituents positioned at the ortho and para locations relative to the hydroxyl group. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.

The strategic placement of fluorine atoms significantly alters the physicochemical properties compared to unsubstituted phenol. This modification enhances metabolic stability and lipophilicity when incorporated into larger molecular structures, making it an invaluable precursor for developing novel pharmaceutical agents and agrochemical formulations. We prioritize rigorous quality control measures to guarantee that every batch meets stringent international standards.

Chemical Properties and Reactivity

The presence of fluorine substituents imparts distinct chemical characteristics to the phenol ring. These features include increased acidity of the hydroxyl proton and modified nucleophilic behavior during substitution reactions. Chemists leverage these properties to facilitate specific coupling reactions and functional group transformations that are otherwise challenging with non-fluorinated analogs.

  • Enhanced thermal stability compared to standard phenolic compounds
  • Improved solubility profiles in various organic solvents
  • Predictable reactivity patterns for scalable synthesis
  • Compatibility with diverse catalytic systems

Industrial Applications

This fluorinated intermediate serves as a foundational component in the synthesis of complex organic molecules. Primary application areas include the development of kinase inhibitors, anti-inflammatory agents, and specialized polymeric materials. The compound's ability to act as a versatile electrophile or nucleophile allows for flexible synthetic routes in multi-step processes.

In the agrochemical sector, 2,4,6-Trifluorophenol derivatives contribute to the efficacy of herbicides and fungicides. The fluorine content often enhances biological activity and environmental persistence profiles, aligning with modern agricultural needs for effective crop protection solutions. Our team provides technical support to optimize integration into your specific formulation workflows.

Quality Specifications

We maintain strict quality assurance protocols throughout production. Each lot undergoes comprehensive analysis using advanced instrumentation such as HPLC and NMR to verify identity and purity. The following table outlines the standard specification parameters for our commercial grade material.

ParameterSpecification
AppearanceWhite to off-white solid
AssayGreater than or equal to 97.0 percent
Moisture ContentLess than or equal to 0.2 percent
Melting Point49 to 51 degrees Celsius
CAS Number2268-17-9

Storage and Handling

Proper storage conditions are essential to maintain product integrity over time. We recommend keeping the material in a cool, ventilated area away from direct sunlight and moisture sources. Containers should remain tightly sealed when not in use to prevent absorption of atmospheric water which could affect performance in moisture-sensitive reactions.

Safety precautions should always be observed during handling. Personnel must wear appropriate personal protective equipment including gloves and eye protection. Refer to the provided Safety Data Sheet for detailed hazard information and emergency procedures. We offer flexible packaging options including 25 kg drums to suit various logistical requirements and bulk ordering needs.