Intermediates

2,4,6-Trimethyliodobenzene

  • CAS No.4028-63-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,4,6-Trimethyliodobenzene (CAS 4028-63-1) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for industrial applications.

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Product Technical Details

Product Overview

2,4,6-Trimethyliodobenzene, frequently referred to in industrial contexts as 2-Iodomesitylene, stands as a pivotal building block within the sphere of advanced organic synthesis and chemical manufacturing. This specialized aryl iodide derivative is distinguished by its unique steric configuration, resulting from the three methyl groups positioned on the benzene ring. Our facility is dedicated to producing this compound with an unwavering focus on high purity, consistency, and reliability to meet the rigorous demands of pharmaceutical research and material science development.

The molecular architecture features an iodine atom situated at the ortho position relative to the methyl substituents, rendering it highly reactive and versatile in transition metal-catalyzed cross-coupling reactions. This specific reactivity profile establishes the compound as an indispensable reagent for constructing complex molecular architectures required in modern chemistry. We adhere to strict quality control protocols throughout the manufacturing process to ensure that every batch consistently meets or exceeds the specified assay requirements for professional use.

Technical Specifications

Our production process is engineered to guarantee a product that aligns with international standards for high-grade chemical intermediates. The physical and chemical properties are tightly monitored using advanced analytical techniques to ensure reliability in downstream processing and reaction efficiency.

Parameter Value
CAS Number 4028-63-1
Molecular Formula C9H11I
Molecular Weight 246.088
Appearance Yellow powder
Assay ≥98.0%
Melting Point 28-32 °C
Boiling Point 244.9±9.0 °C
Density 1.5±0.1 g/cm3

Industrial Applications

This chemical intermediate finds extensive utility in the synthesis of fine chemicals, active pharmaceutical ingredients, and specialized agrochemicals. The steric bulk provided by the mesityl group often imparts significant stability to resulting compounds, a feature that is crucial in ligand design for homogeneous catalysis. Additionally, it is increasingly utilized in the development of organic electronic materials, such as OLEDs, where specific substitution patterns are required to precisely tune electronic and optical properties.

Researchers and process chemists value this compound for its excellent compatibility with palladium and nickel-catalyzed systems. It serves as a reliable electrophile in prominent coupling reactions including Suzuki-Miyaura, Heck, and Sonogashira protocols. Our global manufacturing network ensures that supply chains remain robust and uninterrupted, supporting both pilot-scale experiments and large-scale industrial production runs without compromising on quality.

Quality Assurance and Logistics

We understand that consistency is the cornerstone of successful chemical manufacturing. Each production lot undergoes comprehensive analysis using High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy to verify identity and purity levels. A detailed Certificate of Analysis (COA) is provided with every shipment to document full compliance with specifications and regulatory standards.

For optimal storage, the product should be kept in a cool, ventilated environment away from direct sunlight, moisture, and incompatible materials to maintain long-term stability. We offer flexible packaging options to suit diverse logistical needs, typically supplying 25 kg per drum, but can accommodate custom requirements based on specific client requests. Our dedicated logistics team ensures safe and timely global delivery, adhering to all relevant international transportation regulations for chemical goods.