Intermediates

2,4-Dichlorophenylboronic Acid

  • CAS No.68716-47-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,4-Dichlorophenylboronic Acid designed for pharmaceutical synthesis and organic coupling reactions.

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Product Technical Details

Product Overview

2,4-Dichlorophenylboronic Acid represents a critical organoboron compound extensively utilized in modern organic synthesis and medicinal chemistry. As a specialized arylboronic acid derivative, this chemical serves as a fundamental building block for constructing complex molecular architectures. Our facility produces this intermediate under strict quality control protocols to ensure consistent performance in downstream chemical transformations. The compound is characterized by its stability and reactivity, making it an essential reagent for researchers and industrial manufacturers alike.

We understand the importance of reliability in the supply chain for pharmaceutical development. Therefore, every batch undergoes rigorous analytical testing to verify identity and purity. This commitment to quality ensures that our clients receive materials that meet the demanding specifications required for advanced synthetic applications. Whether used in academic research or large-scale production, this product delivers the performance necessary for successful outcomes.

Technical Specifications

ParameterSpecification
CAS Number68716-47-2
Molecular FormulaC6H5BCl2O2
Molecular Weight190.82 g/mol
AppearanceWhite powder
Assay (Purity)≥98.0%
Water Content≤0.50%
Melting Point246-249 °C
Density1.47 g/cm3
Boiling Point331.3 °C at 760 mmHg

Industrial Applications

This boronic acid derivative is primarily employed as a key intermediate in the synthesis of pharmaceutical compounds and agrochemicals. It plays a pivotal role in palladium-catalyzed cross-coupling reactions, specifically the Suzuki-Miyaura coupling, which is indispensable for forming carbon-carbon bonds. These reactions are fundamental in the creation of biaryl structures found in numerous bioactive molecules. Additionally, the compound is utilized in the preparation of specialized heterocycles and enzyme inhibitor research frameworks.

Our clients leverage this material for developing potential therapeutic agents targeting various biological pathways. The high purity level minimizes side reactions, thereby improving overall yield and simplifying purification processes. By providing a reliable source of this intermediate, we support the efficient progression of drug discovery campaigns from early-stage synthesis to process development. The versatility of this chemical allows for its integration into diverse synthetic routes requiring robust arylating agents.

  • High reactivity in cross-coupling reactions ensures efficient synthesis.
  • Consistent quality supports reproducible research and production results.
  • Low water content enhances stability during storage and handling.
  • Suitable for scale-up from laboratory to industrial manufacturing.
  • Comprehensive documentation supports regulatory compliance needs.

Storage and Handling

To maintain optimal quality, 2,4-Dichlorophenylboronic Acid should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed when not in use to prevent exposure to moisture and air, which could affect stability over extended periods. The product is classified as non-dangerous goods for transport, facilitating straightforward logistics and global shipping. We offer flexible packaging options, including standard 25kg drums, with custom configurations available to meet specific customer requirements. Proper handling procedures should always be followed in accordance with safety data sheets to ensure a safe working environment for all personnel involved in the handling of this chemical substance.