2,4-Difluoro-6-nitroaniline
- CAS No.364-30-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2,4-Difluoro-6-nitroaniline (CAS 364-30-7) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical applications.
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Product Overview
2,4-Difluoro-6-nitroaniline is a specialized fluorinated aromatic compound serving as a critical building block in modern medicinal chemistry and agrochemical development. Characterized by its unique substitution pattern featuring two fluorine atoms and a nitro group on the aniline ring, this intermediate offers exceptional reactivity for nucleophilic aromatic substitution reactions. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for complex synthetic routes requiring precise functional group tolerance.
As a key precursor in the synthesis of various pharmaceutical agents, this compound facilitates the introduction of fluorine atoms which often enhance metabolic stability and bioavailability in final drug products. The strategic positioning of the nitro group allows for versatile downstream transformations, including reduction to amines or conversion into heterocyclic systems. We prioritize strict quality control measures to guarantee that every batch meets rigorous international standards for research and industrial production.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2,4-Difluoro-6-nitroaniline |
| CAS Number | 364-30-7 |
| Molecular Formula | C6H4F2N2O2 |
| Molecular Weight | 174.105 g/mol |
| Appearance | White to light yellow crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 85-87°C |
| Boiling Point | 272.6±35.0°C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 118.7±25.9°C |
Industrial Applications
This fluorinated intermediate is extensively utilized in the preparation of advanced therapeutic compounds, particularly within the realms of oncology and anti-infective research. The presence of fluorine atoms imparts desirable physicochemical properties, such as increased lipophilicity and resistance to enzymatic degradation, which are crucial for optimizing drug candidates. Chemists leverage this building block to construct quinolone antibiotics, kinase inhibitors, and other heterocyclic structures essential for modern pharmacotherapy.
- Pharmaceutical Synthesis: Used as a core scaffold for developing novel small molecule drugs.
- Agrochemical Production: Serves as a precursor for high-performance herbicides and pesticides.
- Material Science: Applied in the creation of specialized polymers and organic electronic materials.
- Research and Development: Essential for laboratory-scale optimization of synthetic pathways.
Quality Assurance and Storage
We maintain a robust quality management system to ensure product integrity from synthesis to delivery. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. To maintain stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures are recommended to ensure safety during industrial processing. Our packaging options include 25 kg drums, with customization available to meet specific logistical requirements for global distribution.
