Intermediates

2,4-Difluoronitrobenzene

  • CAS No.446-35-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,4-Difluoronitrobenzene (CAS 446-35-5) designed for advanced organic synthesis. Reliable supply with ≥99.0% assay for industrial pharmaceutical and agrochemical applications.

Request Bulk Pricing

Product Technical Details

Product Overview

2,4-Difluoronitrobenzene is a highly valuable fluorinated aromatic intermediate widely utilized in the field of advanced organic synthesis. As a critical building block, this compound facilitates the introduction of fluorine atoms into complex molecular structures, enhancing the biological activity and metabolic stability of final products. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for researchers and industrial manufacturers engaged in the development of pharmaceuticals, agrochemicals, and specialized functional materials.

The presence of both nitro and fluoro substituents on the benzene ring provides unique reactivity profiles, particularly in nucleophilic aromatic substitution reactions. This versatility allows chemists to derive a wide range of downstream derivatives with precision. We are committed to supplying this chemical intermediate with consistent quality, supported by rigorous quality control protocols and comprehensive documentation.

Key Specifications

To guarantee performance in sensitive synthesis pathways, we maintain strict control over physical and chemical parameters. The following table outlines the standard specifications for our commercial grade material:

Property Specification
Appearance Pale yellow transparent liquid
Assay (Purity) ≥99.0%
Moisture Content ≤0.2%
Density 1.451 g/cm³
Melting Point 9-10°C
Boiling Point 203-204°C
Refractive Index 1.511
Molecular Formula C6H3F2NO2
Molecular Weight 159.09

Industrial Applications

This fluorinated nitro compound serves as a foundational raw material in multiple high-tech sectors. Its primary use lies in the synthesis of pharmaceutical APIs where fluorine substitution is required to improve drug potency. Additionally, it is extensively used in the agrochemical industry for creating novel pesticides and herbicides with enhanced environmental profiles. Beyond these sectors, it finds application in the production of dyes, polymers, and liquid crystals.

  • Pharmaceutical intermediate for fluoroquinolones and other therapeutic agents
  • Agrochemical synthesis for advanced crop protection solutions
  • Material science applications involving high-performance polymers
  • Research and development for new organic synthesis methodologies

Storage and Handling

Proper storage is essential to maintain the integrity of 2,4-Difluoronitrobenzene. The product should be kept in a cool, ventilated area away from direct sunlight and sources of ignition. Containers must remain tightly sealed when not in use to prevent moisture absorption and contamination. We recommend standard safety precautions during handling, including the use of appropriate personal protective equipment. Our packaging options include 200 kg drums, with custom packaging available upon request to suit specific logistical requirements.