Intermediates

2,4-Difluorophenyl Isothiocyanate

  • CAS No.141106-52-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2,4-Difluorophenyl Isothiocyanate for organic synthesis. Reliable supply with COA and global shipping available.

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Product Technical Details

Product Overview

2,4-Difluorophenyl Isothiocyanate is a highly specialized fluorinated organic compound designed for advanced chemical synthesis applications. As a key member of the aryl isothiocyanate family, this substance features a unique structural configuration that incorporates two fluorine atoms at the ortho and para positions of the phenyl ring. This specific substitution pattern enhances the reactivity and electronic properties of the molecule, making it an invaluable building block for medicinal chemistry and agrochemical research. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding laboratory and industrial environments.

The introduction of fluorine atoms into organic molecules is a critical strategy in modern drug design, often improving metabolic stability and bioavailability. Consequently, this isothiocyanate derivative serves as a pivotal intermediate in the construction of complex heterocyclic systems. It is widely utilized by research institutions and pharmaceutical companies seeking to develop novel therapeutic agents or optimize existing chemical pathways. We commit to providing a reliable supply chain for this essential chemical reagent to support innovation in life sciences.

Key Specifications and Properties

Quality control is paramount in the production of fine chemical intermediates. Each batch of 2,4-Difluorophenyl Isothiocyanate undergoes rigorous analytical testing to verify compliance with established standards. The physical characteristics, including density and boiling point, are carefully monitored to ensure consistency across all shipments. Our quality assurance team implements strict protocols to guarantee that every drum meets the specified assay requirements. Below is a detailed table outlining the technical specifications of our product:

ParameterValue
CAS Number141106-52-7
Molecular FormulaC7H3F2NS
Molecular Weight171.167 g/mol
AppearanceColorless to pale yellow transparent liquid
Assay (Purity)≥99.0%
Density1.3±0.1 g/cm3
Boiling Point224.8±25.0 °C at 760 mmHg
Flash Point89.8±23.2 °C

Industrial Applications and Usage

This chemical intermediate finds extensive utility in the synthesis of various organic compounds. Its primary function lies in its ability to act as an electrophilic reagent, reacting readily with nucleophiles such as amines to form thiourea derivatives. These derivatives are foundational structures in many biologically active molecules. Researchers utilize this product to explore structure-activity relationships in new drug candidates. Additionally, it serves as a precursor in the manufacturing of specialized polymers and agricultural chemicals where fluorinated motifs are required for performance enhancement.

  • Construction of heterocyclic compounds for pharmaceutical research.
  • Synthesis of thiourea-based ligands and catalysts.
  • Development of fluorinated agrochemical active ingredients.
  • Material science applications requiring specific electronic properties.

Storage and Safety Information

Proper handling and storage are essential to maintain the integrity of 2,4-Difluorophenyl Isothiocyanate. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent hydrolysis or contamination. Personnel handling this chemical should wear appropriate personal protective equipment, including gloves and safety goggles, to avoid skin contact or inhalation of vapors. In case of spillage, standard chemical cleanup procedures should be followed immediately to ensure workplace safety.

We offer flexible packaging options, including 200 kg drums, to accommodate various production scales. Our logistics team ensures timely global delivery with full documentation, including Certificates of Analysis (COA). Partner with us for high-quality chemical intermediates that meet your rigorous research and development needs. Our dedicated support team is available to assist with technical inquiries and custom packaging requests.