Intermediates

2,4-Difluorotoluene

  • CAS No.452-76-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,4-Difluorotoluene (CAS 452-76-6) designed for pharmaceutical and agrochemical synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

2,4-Difluorotoluene is a vital fluorinated aromatic compound widely utilized in the synthesis of complex pharmaceutical agents and advanced agrochemical formulations. As a key building block in organic chemistry, this substance features a toluene backbone substituted with fluorine atoms at the second and fourth positions. The presence of fluorine significantly enhances the metabolic stability and lipophilicity of downstream molecules, making it an indispensable precursor in modern medicinal chemistry. Our manufacturing facility adheres to rigorous international standards to ensure consistent quality and purity for every batch produced.

We understand the critical role this intermediate plays in your production pipeline. Therefore, we employ advanced distillation and purification technologies to minimize impurities and maximize yield. Whether you are developing new drug candidates or optimizing existing agricultural solutions, our 2,4-Difluorotoluene provides the reliable foundation necessary for successful chemical synthesis. We are committed to supporting global research and industrial applications with timely delivery and comprehensive technical documentation.

Technical Specifications

ParameterSpecification
Product Name2,4-Difluorotoluene
CAS Number452-76-6
Molecular FormulaC7H6F2
Molecular Weight128.12 g/mol
AppearanceColorless transparent liquid
Purity≥98.0%
Water Content≤0.5%
Density1.12 g/mL at 25 °C
Boiling Point113-117 °C
Refractive Indexn20/D 1.449

Industrial Applications

The versatility of 2,4-Difluorotoluene makes it suitable for a broad range of high-value industrial sectors. In the pharmaceutical industry, it serves as a crucial intermediate for constructing fluorinated active pharmaceutical ingredients (APIs). The unique electronic properties of the fluorine substituents allow chemists to fine-tune the biological activity and pharmacokinetic profiles of new therapeutic compounds. Additionally, this chemical is extensively used in the agrochemical sector for the development of herbicides and pesticides that require enhanced environmental stability.

Beyond traditional chemistry, this compound finds application in the emerging field of organic light-emitting diodes (OLED). High-purity fluorinated aromatics are essential for creating efficient electron-transport materials and host materials in display technologies. Our product meets the stringent purity requirements necessary for these sensitive electronic applications. We support clients across these diverse industries with tailored solutions that address specific synthesis challenges and performance benchmarks.

Quality Assurance and Storage

Quality control is paramount in our production process. Every batch of 2,4-Difluorotoluene undergoes comprehensive testing using gas chromatography and other analytical methods to verify compliance with specified parameters. We provide a Certificate of Analysis (COA) with each shipment to ensure transparency and traceability. Proper storage is essential to maintain the integrity of the chemical. The product should be stored in a cool, dry, and well-ventilated area away from direct sunlight and heat sources.

Containers must remain tightly closed when not in use to prevent contamination and moisture absorption. As a flammable liquid, appropriate safety measures should be implemented during handling and transport according to local regulations. We offer flexible packaging options, including plastic drums and plastic-coated iron drums, to suit various logistical needs. Our global supply chain ensures that you receive your materials promptly, minimizing downtime in your manufacturing operations. Contact our technical team for detailed safety data sheets and customization options.