2,5-Bis(trifluoromethyl)bromobenzene
- CAS No.7617-93-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity fluorinated intermediate designed for advanced pharmaceutical synthesis. Offers excellent stability and reactivity for complex organic transformations.
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Product Overview
2,5-Bis(trifluoromethyl)bromobenzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern medicinal chemistry and advanced organic synthesis. Characterized by the presence of two trifluoromethyl groups and a bromine substituent on the benzene ring, this molecule offers unique electronic and steric properties that are essential for developing next-generation pharmaceutical agents. Our manufacturing process ensures exceptional batch-to-batch consistency, making it a reliable choice for research and industrial scale production.
The introduction of trifluoromethyl groups into organic molecules is a strategic move in drug design, often enhancing metabolic stability, lipophilicity, and bioavailability. As a key intermediate, this compound facilitates cross-coupling reactions and other transformative chemical processes required to construct complex active pharmaceutical ingredients (APIs). We adhere to strict quality control protocols to guarantee that every shipment meets the rigorous demands of the global pharmaceutical supply chain.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2,5-Bis(trifluoromethyl)bromobenzene |
| CAS Number | 7617-93-8 |
| Molecular Formula | C8H3BrF6 |
| Molecular Weight | 293.00 g/mol |
| Appearance | Colorless to Pale Yellow Liquid |
| Purity | ≥99.0% |
| Boiling Point | 146-147 °C |
| Density | 1.691 g/cm3 |
| Refractive Index | 1.434 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the synthesis of complex pharmaceutical compounds and agrochemicals. Its reactivity profile makes it particularly suitable for palladium-catalyzed coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. Chemists value this substrate for its ability to introduce fluorine atoms into specific positions of a molecular scaffold, which is often a rate-limiting step in the development of novel therapeutics.
Beyond pharmaceuticals, this compound finds utility in the creation of advanced materials and liquid crystals where specific dielectric properties are required. The high purity level ensures minimal side reactions during synthesis, thereby improving overall yield and reducing downstream purification costs. Our team provides technical support to help clients optimize their synthesis routes for maximum efficiency and safety.
Quality and Safety
We understand that handling fluorinated compounds requires strict adherence to safety guidelines. This product should be stored in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents. Containers must remain tightly closed to prevent moisture absorption and contamination. We recommend using appropriate personal protective equipment, including gloves and eye protection, during handling procedures.
Every batch is accompanied by a comprehensive Certificate of Analysis (COA) verifying identity, purity, and physical constants. Our facility operates under comprehensive quality management systems to ensure compliance with international standards. For large-scale requirements, we offer flexible packaging solutions tailored to customer logistics needs. Partner with us for a reliable supply of high-performance chemical intermediates that drive innovation in your research and development projects.
