2,5-Dichlorothiophene
- CAS No.3172-52-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,5-Dichlorothiophene liquid for pharmaceutical synthesis. Ideal intermediate for Brinzolamide production with strict QC.
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Product Overview
2,5-Dichlorothiophene is a specialized heterocyclic organic compound widely recognized for its critical role in advanced pharmaceutical synthesis and chemical research. As a key chemical building block, this substance serves as an essential precursor in the manufacturing of various therapeutic agents, including specific antiglaucoma medications. Our facility produces this compound under strict quality control standards to ensure consistent molecular integrity and high purity levels suitable for sensitive chemical reactions and industrial scaling.
The compound exists as a colorless to light yellow liquid at standard temperature and pressure. Its unique chemical structure, featuring a thiophene ring substituted with chlorine atoms at the 2 and 5 positions, provides excellent reactivity for nucleophilic substitution and cross-coupling reactions. This makes it an invaluable asset for research laboratories and industrial production lines focused on developing complex organic molecules with high precision.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 3172-52-9 |
| Molecular Formula | C4H2Cl2S |
| Molecular Weight | 153.030 g/mol |
| Appearance | Colorless to light yellow liquid |
| Purity (GC) | ≥98.0% |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 158.9±20.0 °C at 760 mmHg |
| Melting Point | -41 to -40 °C |
| Flash Point | 59.4±0.0 °C |
| Vapour Pressure | 3.3±0.3 mmHg at 25°C |
| Index of Refraction | 1.584 |
Industrial Applications
The primary application of 2,5-Dichlorothiophene lies in the pharmaceutical sector, specifically as a vital intermediate in the synthesis of Brinzolamide. Brinzolamide is a carbonic anhydrase inhibitor used to treat elevated intraocular pressure in patients with glaucoma. The high purity of our intermediate ensures that downstream synthesis processes yield final products that meet rigorous pharmacopeial standards. Beyond this specific application, the compound is utilized in broader organic synthesis projects involving heterocyclic chemistry and material science.
- Pharmaceutical intermediate for antiglaucoma drugs.
- Reagent for heterocyclic compound synthesis.
- Building block for agrochemical research.
- Material for advanced organic chemistry studies.
- Component in specialized polymer development.
Quality Assurance and Packaging
We understand that consistency is paramount in chemical manufacturing. Every batch of 2,5-Dichlorothiophene undergoes comprehensive testing using Gas Chromatography (GC) to verify assay levels above 98.0%. A Certificate of Analysis (COA) is provided with every shipment to document physical and chemical properties. Our packaging solutions are designed to maintain stability during transit, typically available in 200 kg drums, with customization options available to meet specific logistical requirements and customer needs.
Safety and Storage Guidelines
Proper handling and storage are essential to maintain the quality of this chemical. It should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. The container must remain tightly closed when not in use to prevent moisture absorption or contamination. Personnel handling this substance should adhere to standard laboratory safety protocols, including the use of appropriate personal protective equipment to ensure workplace safety.
