Intermediates

2,5-Difluorobenzyl Chloride

  • CAS No.495-07-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,5-Difluorobenzyl Chloride for advanced organic synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

2,5-Difluorobenzyl Chloride is a highly valued fluorinated organic intermediate widely utilized in modern chemical synthesis. As a key building block, it plays an essential role in the development of complex molecular structures required for pharmaceuticals, agrochemicals, and advanced material science. Our facility produces this compound under strict quality control standards to ensure consistent performance in downstream reactions.

The presence of fluorine atoms at the 2 and 5 positions of the benzyl ring significantly enhances the metabolic stability and lipophilicity of final products. This makes 2,5-Difluorobenzyl Chloride an indispensable reagent for medicinal chemists aiming to optimize drug candidates. We are committed to supplying this critical intermediate with high purity and reliability to support global research and industrial production needs.

Technical Specifications

ParameterValue
Chemical Name2,5-Difluorobenzyl Chloride
CAS Number495-07-8
Molecular FormulaC7H5ClF2
Molecular Weight162.56 g/mol
AppearanceColorless clear liquid
Assay≥98.0%
Density1.294 g/cm³
Boiling Point173.5°C
Flash Point61.3°C
Refractive Index1.485

Industrial Applications

This fluorinated benzyl chloride serves as a versatile precursor in various synthetic pathways. In the pharmaceutical sector, it is frequently employed in the synthesis of kinase inhibitors and other therapeutic agents where fluorine substitution is crucial for bioavailability. The compound acts as an electrophile in nucleophilic substitution reactions, allowing for the efficient introduction of the 2,5-difluorobenzyl moiety into target molecules.

Beyond pharmaceuticals, 2,5-Difluorobenzyl Chloride finds applications in agrochemical development, contributing to the creation of novel pesticides and herbicides with improved environmental profiles. Additionally, it is used in the production of specialized polymers and liquid crystals, where its unique electronic properties enhance material performance. Our team provides technical support to help customers integrate this intermediate into their specific manufacturing processes.

Quality Assurance and Safety

Quality is paramount in our production process. Every batch of 2,5-Difluorobenzyl Chloride undergoes rigorous testing using advanced analytical techniques such as GC, HPLC, and NMR to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with international standards. Our manufacturing facility adheres to strict safety protocols to minimize environmental impact and ensure worker safety.

Regarding handling, this chemical should be managed in a well-ventilated area with appropriate personal protective equipment. It is sensitive to moisture and should be stored in tightly closed containers away from incompatible substances. Proper storage conditions help maintain the stability and integrity of the product over time, ensuring it performs as expected in your synthesis routes.

Packaging and Logistics

We understand the importance of secure and efficient logistics in the global supply chain. 2,5-Difluorobenzyl Chloride is typically packaged in 200 kg drums, though we offer flexible packaging solutions tailored to specific customer requirements. Our logistics partners ensure timely delivery to destinations worldwide, maintaining the cold chain or specific storage conditions if necessary. Whether you require small-scale samples for research or bulk quantities for industrial production, we are equipped to meet your demands with competitive pricing and reliable service.