2,6-Dichloro-3-fluoroacetophenone

Product Overview

2,6-Dichloro-3-fluoroacetophenone is a highly specialized fluorinated aromatic ketone that serves as a critical building block in modern medicinal chemistry and advanced organic synthesis. The unique substitution pattern featuring both chlorine and fluorine atoms on the phenyl ring imparts distinct electronic and steric properties, making it an invaluable precursor for the development of novel pharmaceutical agents and agrochemical compounds. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and production environments.

This compound is particularly valued for its reactivity in nucleophilic substitution reactions and cross-coupling processes. The presence of the fluorine atom enhances metabolic stability in downstream drug candidates, while the chloro groups provide versatile handles for further functionalization. We supply this material to meet the rigorous standards required by global pharmaceutical companies and research institutions. The molecular structure allows for diverse synthetic transformations, enabling chemists to construct complex molecular architectures with precision and efficiency.

Technical Specifications

Industrial Applications

The primary application of 2,6-Dichloro-3-fluoroacetophenone lies in the synthesis of complex organic molecules. It is frequently employed as an intermediate in the production of kinase inhibitors and other targeted therapeutics. Additionally, it finds utility in the agrochemical sector for creating robust crop protection agents. The high assay value of ≥98.0% ensures minimal impurity interference during sensitive synthetic steps, reducing the need for extensive purification downstream.

In pharmaceutical development, fluorinated intermediates are essential for optimizing the pharmacokinetic profiles of drug candidates. This specific acetophenone derivative facilitates the introduction of key pharmacophores into lead compounds. Its stability under various reaction conditions makes it a reliable choice for multi-step synthesis routes. Researchers rely on its consistent performance to accelerate drug discovery timelines and reduce development risks associated with variable raw material quality. The compound supports diverse chemical transformations including halogen exchange and carbonyl modifications.

Quality Assurance and Packaging

Quality control is paramount in our operations. Each batch undergoes comprehensive testing using advanced analytical techniques such as HPLC and GC-MS to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to guarantee compliance with specifications. Packaging is designed to maintain product integrity during transit, with options available for bulk industrial requirements. Standard packaging includes 200 kg drums, but we accommodate custom requests to suit specific logistical needs.

We understand the importance of supply chain reliability. Our facility adheres to strict ISO standards for chemical manufacturing and handling. Customers can request custom packaging configurations to suit their specific logistical needs, ranging from standard drums to specialized containers for hazardous materials. Documentation support is available to assist with regulatory compliance in various international markets, ensuring smooth customs clearance and receipt.

Storage and Safety

To maintain optimal stability, this chemical should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. Standard laboratory safety protocols should be followed during handling, including the use of appropriate personal protective equipment. Proper storage conditions ensure the longevity and performance of the product throughout its shelf life. Avoid exposure to strong oxidizing agents and moisture to prevent degradation.

Safety data sheets (SDS) are provided upon request to ensure safe handling practices are implemented across your organization. We recommend consulting with safety officers before large-scale usage to establish appropriate engineering controls. Our commitment to safety extends beyond the product itself, encompassing responsible manufacturing practices and environmental stewardship throughout the production lifecycle. Contact our technical support team for detailed handling guidelines and risk assessment information.