2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile
- CAS No.82671-02-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in the synthesis of fluoroquinolone antibiotics like Gemifloxacin. Available in bulk quantities with comprehensive COA.
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Product Overview
2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile is a specialized heterocyclic compound designed for advanced pharmaceutical synthesis. This fluorinated pyridine derivative serves as a critical building block in the production of next-generation therapeutic agents. Our manufacturing process ensures exceptional chemical stability and consistency, making it an ideal choice for research and development teams focused on antibiotic formulation.
The compound features a unique substitution pattern on the pyridine ring, incorporating both chloro and fluoro functional groups alongside a nitrile moiety. This specific arrangement facilitates selective nucleophilic substitution reactions, which are essential for constructing complex molecular architectures found in modern medicine. We prioritize strict quality control measures to guarantee that every batch meets the rigorous demands of the pharmaceutical industry.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 82671-02-1 |
| Molecular Formula | C6HCl2FN2 |
| Molecular Weight | 190.99 g/mol |
| Appearance | Off-white to light tan crystalline powder |
| Purity | ≥98.0% |
| Melting Point | 89-91 °C |
| Loss on Drying | ≤1.0% |
| Iron Ion Content | ≤20 PPM |
Industrial Applications
This intermediate is primarily utilized in the synthesis of Gemifloxacin mesylate, a potent fluoroquinolone antibiotic used to treat various bacterial infections. The high purity level of our product minimizes side reactions during the coupling process, thereby improving overall yield and reducing purification costs for downstream manufacturers. Beyond its primary application, this chemical serves as a valuable precursor in the development of other heterocyclic pharmaceuticals and agrochemicals.
Research laboratories leverage this compound for structure-activity relationship studies due to its reactive sites. The presence of the nitrile group allows for further functionalization into amides or amines, providing versatility in synthetic routes. Our global clientele relies on this material for scaling up production from pilot batches to commercial manufacturing volumes.
Quality Assurance and Safety
We adhere to international quality management standards to ensure product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing test results for purity, identity, and impurities. Our quality control team employs high-performance liquid chromatography (HPLC) and gas chromatography (GC) to verify specifications before release.
Regarding safety, this chemical should be handled in a well-ventilated environment using appropriate personal protective equipment. It is classified as a stable compound under normal conditions but should be kept away from strong oxidizing agents. Proper storage in a cool, dry, and well-closed container protects the material from moisture and light degradation, ensuring long-term stability.
Packaging and Logistics
Standard packaging consists of 25kg cardboard drums lined with polyethylene bags to prevent contamination and moisture ingress. We also offer customized packaging solutions based on specific customer requirements and logistical constraints. Our supply chain team ensures timely global delivery with comprehensive documentation to facilitate smooth customs clearance. Partner with us for reliable supply chain solutions and technical support tailored to your synthesis needs.
