Intermediates

2,6-Dichloro-5-fluoropyridin-3-amine

  • CAS No.152840-65-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,6-Dichloro-5-fluoropyridin-3-amine (CAS 152840-65-8) available for pharmaceutical synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

2,6-Dichloro-5-fluoropyridin-3-amine is a specialized fluorinated heterocyclic compound serving as a critical building block in modern medicinal chemistry. Identified by CAS number 152840-65-8, this chemical features a pyridine ring substituted with chloro, fluoro, and amino groups. These specific substituents provide unique reactivity profiles, making the compound highly valuable for the synthesis of complex pharmaceutical intermediates and advanced organic molecules.

Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications. The presence of halogen atoms at the 2 and 6 positions allows for versatile nucleophilic substitution reactions, while the amino group at the 3 position offers additional functionalization opportunities. This molecular architecture is essential for developing novel therapeutic agents and agrochemical products.

Specifications and Physical Properties

We adhere to strict quality control standards to guarantee the performance of this chemical in your synthesis pathways. The following table outlines the key technical parameters and physical characteristics verified during our quality assurance process.

ParameterValue
Chemical Name2,6-Dichloro-5-fluoropyridin-3-amine
CAS Number152840-65-8
Molecular FormulaC5H3Cl2FN2
Molecular Weight180.99 g/mol
AppearanceYellow solid
Purity≥98.0%
Boiling Point295.7±35.0 °C at 760 mmHg
Flash Point132.7±25.9 °C
Density1.6±0.1 g/cm3
Refractive Index1.594

Industrial Applications

This fluorinated pyridine derivative is primarily utilized as a key intermediate in the pharmaceutical industry. Its structure facilitates the construction of kinase inhibitors and other biologically active molecules. The chemical stability and reactivity balance make it an ideal candidate for multi-step synthesis routes requiring precise functional group manipulation.

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs).
  • Organic Synthesis: Serves as a versatile building block for heterocyclic chemistry.
  • Agrochemical Research: Applicable in the development of novel crop protection agents.
  • Chemical Research: Employed in academic and industrial laboratories for method development.

Quality Assurance and Storage

Every batch of 2,6-Dichloro-5-fluoropyridin-3-amine is accompanied by a Certificate of Analysis (COA) to verify compliance with specified purity standards. We employ advanced analytical techniques including HPLC and NMR to confirm structural integrity and impurity profiles. Proper storage is essential to maintain product stability over time.

Store this material in a tightly closed container within a cool, dry environment. Avoid exposure to moisture and direct sunlight to prevent degradation. Our packaging options include 25 kg drums, ensuring safe transport and handling for bulk orders. As a global manufacturer, we are committed to providing reliable supply chains and technical support for all our clients.