Intermediates

2,6-Difluoroanisole

  • CAS No.437-82-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,6-Difluoroanisole (CAS 437-82-1) designed for advanced organic synthesis applications. Available in bulk with certified quality assurance.

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Product Technical Details

Product Overview

2,6-Difluoroanisole represents a critical class of fluorinated aromatic ethers utilized extensively within the fine chemical and pharmaceutical sectors. As a specialized intermediate, this compound offers unique reactivity profiles due to the strategic positioning of fluorine atoms on the aromatic ring. Our facility produces this material under strict quality control protocols to ensure consistency across large-scale batches. The introduction of fluorine substituents often enhances metabolic stability and lipophilicity in downstream drug candidates, making this anisole derivative a valuable asset for medicinal chemistry programs.

We understand the demanding requirements of modern synthetic pathways. Therefore, our manufacturing process focuses on maximizing yield while minimizing impurities. The resulting product provides a reliable foundation for complex multi-step syntheses. Whether used in the development of novel agrochemicals or pharmaceutical active ingredients, this chemical building block delivers the performance necessary for high-stakes research and production environments.

Technical Specifications

Our quality assurance team verifies every batch against rigorous internal standards that often exceed industry norms. The following table outlines the key physical and chemical parameters guaranteed for this product.

Parameter Specification
CAS Number 437-82-1
Molecular Formula C7H6F2O
Molecular Weight 144.12 g/mol
Appearance Colorless transparent liquid
Assay (Purity) ≥99.0%
Moisture Content ≤0.2%
Density 1.221 g/cm³
Boiling Point 70-72°C
Flash Point 61°C
Refractive Index 1.452

Industrial Applications

This fluorinated intermediate serves as a versatile precursor in various organic synthesis routes. Its primary utility lies in the construction of more complex molecular architectures where fluorine substitution is required to modulate electronic properties. Chemists value this compound for its stability and predictable reactivity during nucleophilic aromatic substitution reactions.

  • Pharmaceutical intermediate synthesis for targeted therapies.
  • Agrochemical development requiring enhanced environmental stability.
  • Material science applications involving fluorinated polymers.
  • Custom synthesis projects demanding high purity starting materials.

Quality Assurance And Storage

Every shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing the specific test results for that batch. We employ advanced analytical techniques including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) to confirm identity and purity. Proper storage is essential to maintain product integrity over time. We recommend storing this material in a cool, ventilated place away from direct sunlight and incompatible substances. Containers should remain tightly sealed when not in use to prevent moisture absorption. Our logistics team ensures safe packaging using industry-standard drums, with options for customized packaging upon request to suit specific supply chain needs.