Intermediates

2,6-Difluorobenzyl Bromide

  • CAS No.85118-00-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,6-Difluorobenzyl Bromide (CAS 85118-00-9) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

2,6-Difluorobenzyl Bromide is a highly valued fluorinated aromatic compound serving as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern, this chemical intermediate enables the introduction of difluorobenzyl moieties into complex molecular structures. The presence of fluorine atoms significantly enhances the metabolic stability and lipophilicity of downstream products, making this compound particularly essential in medicinal chemistry and agrochemical development. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial scale applications.

As a trusted global manufacturer, we prioritize the production of fine chemicals that meet rigorous international standards. This product is synthesized under controlled conditions to minimize impurities and ensure batch-to-batch reproducibility. Whether used for laboratory-scale research or large-scale production, 2,6-Difluorobenzyl Bromide provides a reliable foundation for creating advanced functional materials and therapeutic candidates.

Technical Specifications

Quality control is paramount in the supply of sensitive chemical intermediates. Each batch undergoes comprehensive analysis using gas chromatography and other advanced analytical techniques to verify compliance with specified parameters. The following table outlines the key physical and chemical properties associated with this product.

ParameterSpecification
CAS Number85118-00-9
Molecular FormulaC7H5BrF2
Molecular Weight207.02 g/mol
Purity (GC)≥99.0%
AppearanceOff-white crystalline solid
Melting Point52-55°C
Boiling Point184.9°C
Density1.6 g/cm3
Refractive Index1.522

Industrial Applications

The primary application of 2,6-Difluorobenzyl Bromide lies in its utility as a versatile intermediate for organic synthesis. It is extensively utilized in the pharmaceutical industry for the development of novel drug candidates where fluorination is required to improve bioavailability. Additionally, this compound serves as a key precursor in the synthesis of agrochemicals, including herbicides and pesticides, where specific structural motifs are necessary for biological activity. Material science researchers also employ this building block to create specialized polymers and liquid crystals with enhanced thermal and chemical stability.

Our clients benefit from the high reactivity of the benzyl bromide functionality, which facilitates various substitution reactions. The ortho-fluine substituents provide steric and electronic effects that can be leveraged to direct subsequent chemical transformations. This makes the compound an invaluable asset for chemists designing multi-step synthesis routes for complex target molecules.

Quality Assurance and Packaging

We maintain a robust quality management system to ensure that every shipment meets the agreed specifications. A Certificate of Analysis (COA) is provided with each batch, detailing the results of all quality control tests. Standard packaging consists of 25 kg drums, which are designed to protect the product from moisture and physical damage during transit. However, we understand that different projects have varying requirements, and we offer custom packaging solutions upon request to accommodate specific logistical needs.

Storage and Handling

To maintain the integrity of 2,6-Difluorobenzyl Bromide, proper storage conditions are essential. The product should be stored in a cool, ventilated place away from direct sunlight and sources of ignition. Containers must be kept tightly closed when not in use to prevent exposure to moisture, which could lead to hydrolysis. Personnel handling this chemical should adhere to standard safety protocols, including the use of appropriate personal protective equipment. By following these guidelines, users can ensure safe handling and optimal performance of the material in their respective applications.