Intermediates

2,6-Difluoronitrobenzene

  • CAS No.19064-24-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2,6-Difluoronitrobenzene (CAS 19064-24-5), a key fluorinated aromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.

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Product Technical Details

Product Overview

2,6-Difluoronitrobenzene is a high-value fluorinated aromatic compound widely employed as a critical building block in the synthesis of complex organic molecules. With its dual ortho-fluorine substitution and electron-withdrawing nitro group, this intermediate offers unique reactivity and regioselectivity, making it indispensable in modern medicinal chemistry and crop protection agent development.

Specifications

Molecular FormulaC6H3F2NO2
Molecular Weight159.090 g/mol
Density1.5 ± 0.1 g/cm³
Boiling Point220.1 ± 20.0 °C at 760 mmHg
Flash Point94.1 ± 10.1 °C
Vapour Pressure0.2 ± 0.4 mmHg at 25 °C
Refractive Index1.510
AppearanceYellow powder
Assay≥98.0%

Industrial Applications

As a versatile fluoroaromatic intermediate, 2,6-Difluoronitrobenzene serves as a foundational scaffold in multi-step syntheses. Its primary applications include:

  • Pharmaceutical R&D: Enables construction of fluorinated heterocycles and bioactive cores found in CNS agents, kinase inhibitors, and anti-infective candidates.
  • Agrochemical Innovation: Used to develop next-generation herbicides and insecticides where fluorine enhances metabolic stability and target affinity.
  • Advanced Materials: Contributes to liquid crystals and electronic polymers requiring precise steric and electronic tuning.

Manufactured under stringent quality control protocols, our product meets global regulatory standards for industrial-scale chemical production. Packaging is available in standard 25 kg drums or customized configurations upon request. Store in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.