2,8-Bis(trifluoromethyl)-1H-quinolin-4-one
- CAS No.35853-41-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2,8-Bis(trifluoromethyl)-1H-quinolin-4-one intermediate. Ideal for pharmaceutical synthesis with verified COA and global shipping capabilities.
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Product Overview
2,8-Bis(trifluoromethyl)-1H-quinolin-4-one is a specialized fluorinated organic compound designed for advanced pharmaceutical research and development. As a critical building block in medicinal chemistry, this quinoline derivative features dual trifluoromethyl groups that enhance metabolic stability and lipophilicity in downstream drug candidates. Our manufacturing process ensures consistent quality suitable for complex organic synthesis pathways.
This compound serves as a vital precursor in the production of various therapeutic agents. The introduction of fluorine atoms at the 2 and 8 positions of the quinoline ring system significantly alters the electronic properties of the molecule, making it an invaluable tool for chemists aiming to optimize biological activity and pharmacokinetic profiles in new drug entities.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 35853-41-9 |
| Molecular Formula | C11H5F6NO |
| Molecular Weight | 281.15 g/mol |
| Appearance | Light gray powder |
| Purity | ≥98.0% |
| Water Content | ≤0.5% |
| Melting Point | 130-134 °C |
| Boiling Point | 305.9 °C at 760 mmHg |
| Density | 1.5 ±0.1 g/cm3 |
Quality Assurance and Control
We adhere to strict quality management systems to guarantee the reliability of every batch. Each production lot undergoes rigorous analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. This ensures that the structural integrity and purity levels meet the demanding standards required for pharmaceutical intermediate applications.
- Comprehensive Certificate of Analysis (COA) provided with every shipment.
- Batch traceability maintained from raw materials to final packaging.
- Regular stability testing to confirm shelf-life specifications.
- Custom packaging options available to suit specific laboratory or plant needs.
Industrial Applications
Primarily utilized as a key intermediate in the synthesis of advanced pharmaceutical compounds, this material plays a crucial role in the manufacturing pathway of specific therapeutic agents. Its unique chemical structure allows for versatile functionalization, enabling chemists to construct complex molecular architectures efficiently. It is particularly noted for its utility in the synthesis pathway related to osteoporosis therapeutics, demonstrating its value in bone health research.
Storage and Handling
To maintain optimal chemical stability, 2,8-Bis(trifluoromethyl)-1H-quinolin-4-one should be stored in a tightly sealed container away from direct sunlight and moisture. The recommended storage environment is a cool, dry place with adequate ventilation. Personnel handling this material should follow standard laboratory safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles to prevent inhalation or skin contact.
For bulk orders, we offer flexible packaging solutions including 25kg cardboard drums or customized containers based on client requirements. Our logistics network ensures safe and timely global delivery, supporting your research and production schedules with minimal disruption.
