Intermediates

2-Acetyl-6-methoxynaphthalene

  • CAS No.3900-45-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Acetyl-6-methoxynaphthalene designed for pharmaceutical synthesis. Reliable supply for Naproxen production with full quality documentation.

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Product Technical Details

Product Overview

2-Acetyl-6-methoxynaphthalene is a specialized organic compound widely recognized within the pharmaceutical industry as a critical building block. This substance serves as a key intermediate in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), specifically playing an essential role in the production chain of Naproxen sodium. Our manufacturing facility adheres to strict quality control protocols to ensure that every batch meets the rigorous demands of modern API production.

Chemically identified by the CAS registry number 3900-45-6, this naphthalene derivative exhibits stable physical properties suitable for large-scale industrial processing. The molecular structure allows for efficient downstream functionalization, making it a preferred choice for chemical engineers and procurement specialists looking for reliability in their supply chain. We prioritize consistency in molecular weight and purity profiles to support seamless integration into your synthesis routes.

Technical Specifications

Quality assurance is the cornerstone of our production process. Each lot undergoes comprehensive analytical testing using gas chromatography and other validated methods to confirm identity and purity levels. The following table outlines the standard specification parameters and typical test results observed in our recent production batches.

Items of AnalysisStandard of AnalysisTest Results
AppearanceLight yellow crystalline powderConform
Purity (GC)≥99.0%99.94%
2-Methoxynaphthalene≤0.5%0.02%
1-Acetyl-2-methoxynaphthalene≤0.5%0.01%
1,6-Diacetyl-2-methoxynaphthalene≤0.5%ND
1,1’-Dinaphthalene-2,2’-dimethoxy≤0.5%ND
Total unknown impurities≤0.5%0.03%
Loss on drying≤0.3%0.14%
ConclusionConforms to Factory Standard

Industrial Applications

The primary application of 2-Acetyl-6-methoxynaphthalene is within the pharmaceutical sector, specifically as a precursor for Naproxen sodium (CAS 26159-34-2). The high purity grade we supply ensures minimal byproduct formation during subsequent reaction steps, which is vital for maintaining overall yield and reducing purification costs downstream. Beyond direct API synthesis, this compound may also be utilized in research and development settings for creating novel analogues or studying structure-activity relationships in naphthalene-based therapeutics.

Our clients value this material for its consistent reactivity and low impurity profile. By minimizing contaminants such as residual solvents or isomeric byproducts, we help manufacturers streamline their regulatory filings and ensure final product safety. This level of quality is essential for companies operating under strict Good Manufacturing Practice (GMP) guidelines.

Quality Assurance and Storage

To maintain the integrity of the chemical structure, proper storage conditions are essential. The product should be kept in a tightly closed container within a cool, dry, and well-ventilated area. It is important to store the material away from incompatible substances such as strong oxidizing agents to prevent degradation. Our standard packaging includes 25kg cardboard drums, though we can accommodate custom packaging requirements based on specific logistical needs or safety regulations.

We provide a Certificate of Analysis (COA) with every shipment, detailing the specific batch data including melting point, refractive index, and chromatographic purity. Our logistics team ensures secure global shipping, handling all necessary documentation for international customs clearance. Partnering with us means gaining access to a reliable supply chain backed by two decades of industry expertise and a commitment to chemical safety and compliance.