Intermediates

2-Amino-1,3-propanediol

  • CAS No.534-03-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Amino-1,3-propanediol (Serinol) CAS 534-03-2 for pharmaceutical synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

2-Amino-1,3-propanediol, widely recognized in the chemical industry by its common name Serinol, represents a critical multifunctional building block within the realm of advanced organic synthesis. This versatile amino alcohol serves as a foundational precursor for numerous high-value pharmaceutical compounds and fine chemical applications. Our facility specializes in the production of this key intermediate, adhering to strict quality management systems to ensure consistency across large-scale batches. The compound is characterized by its dual functional groups, which facilitate diverse chemical transformations essential for modern medicinal chemistry.

As a leading global manufacturer, we understand the stringent requirements of the pharmaceutical supply chain. Our 2-Amino-1,3-propanediol is produced under controlled conditions to minimize impurities and maximize yield. The material is particularly valued for its stability and reactivity profile, making it an ideal candidate for complex synthesis routes involving heterocyclic formation and chiral modifications. We commit to providing transparent documentation and robust technical support for all our industrial partners.

Technical Specifications

ParameterSpecification
CAS Number534-03-2
Chemical FormulaC3H9NO2
Molecular Weight91.11 g/mol
AppearanceWhite crystalline solid
Assay (Purity)≥99.0%
Water Content≤0.50%
Melting Point52-55 °C
Boiling Point266.7±20.0 °C
Refractive Index1.496
Unspecified Impurity≤0.50%

Industrial Applications

The primary utility of 2-Amino-1,3-propanediol lies in its role as a strategic intermediate for the synthesis of active pharmaceutical ingredients (APIs). It is notably employed in the manufacturing process of Iopamidol, a non-ionic contrast media used in diagnostic imaging, and Voglibose, an anti-diabetic agent. The high purity levels we maintain are crucial for these downstream applications, where trace impurities can affect the safety and efficacy of the final medical product.

Furthermore, this chemical serves as a vital component in research and development for novel enzyme inhibitors. Specifically, it is utilized in the synthesis of potent inhibitors targeting human uridine phosphorylase. These research applications aim to optimize therapeutic windows, such as reducing the toxicity of certain chemotherapeutic agents like 5-fluorouracil without compromising their antitumor activity. Our product supports both commercial manufacturing and advanced laboratory research initiatives.

Quality Assurance and Safety

Quality control is paramount in our production workflow. Every batch of 2-Amino-1,3-propanediol undergoes rigorous analytical testing using high-performance liquid chromatography (HPLC) and gas chromatography (GC) to verify compliance with stated specifications. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our manufacturing processes are designed to ensure industrial purity levels that meet or exceed international standards for pharmaceutical intermediates.

Regarding safety and handling, this substance is classified under Hazard Class 8. It should be handled with appropriate personal protective equipment in a well-ventilated environment. Our packaging solutions are designed to maintain integrity during transit, preventing moisture absorption and contamination. We adhere to all relevant transportation regulations, including proper labeling and documentation for hazardous materials.

Storage and Packaging

To preserve the stability and quality of 2-Amino-1,3-propanediol, proper storage conditions are essential. The product should be stored in a cool, ventilated warehouse away from direct sources of fire and heat. The ambient temperature should not exceed 37 degrees Celsius to prevent degradation or physical changes to the crystalline structure. We recommend keeping the containers tightly sealed when not in use to minimize exposure to atmospheric moisture.

Standard packaging consists of 25 kg barrels, which are optimized for safe handling and logistics efficiency. However, we recognize that different clients have varying requirements. Therefore, we offer flexible packaging solutions according to customer specifications. Whether you require bulk quantities for large-scale production or smaller units for pilot studies, our logistics team ensures timely and secure global delivery. Contact our sales department for detailed information on bulk pricing and lead times.