2-Amino-3-(trifluoromethyl)pyridine
- CAS No.183610-70-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-Amino-3-(trifluoromethyl)pyridine intermediate for organic synthesis. Reliable supply with comprehensive COA.
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Product Overview
2-Amino-3-(trifluoromethyl)pyridine represents a critical fluorinated heterocyclic building block extensively utilized in modern medicinal chemistry and advanced organic synthesis. As a specialized intermediate, this compound offers unique electronic properties due to the presence of the trifluoromethyl group adjacent to the amino functionality on the pyridine ring. Our manufacturing process ensures high chemical purity and consistency, making it an ideal candidate for complex molecular construction in research and industrial settings.
The incorporation of fluorine atoms into pharmaceutical scaffolds is a well-established strategy to enhance metabolic stability, lipophilicity, and bioavailability of drug candidates. This specific pyridine derivative serves as a versatile precursor for developing novel therapeutic agents, agrochemicals, and functional materials. We maintain strict quality control protocols to guarantee that every batch meets rigorous international standards for research and industrial application, ensuring reliability for your downstream processes.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 183610-70-0 |
| Molecular Formula | C6H5F3N2 |
| Molecular Weight | 162.113 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 70-72 ºC |
| Boiling Point | 203.2±35.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 76.7±25.9 °C |
| Refractive Index | 1.479 |
Industrial Applications
This fluorinated pyridine intermediate is primarily employed in the synthesis of pharmaceutical active ingredients (APIs) where structural modification is required to optimize drug performance. The electron-withdrawing nature of the trifluoromethyl group influences the reactivity of the amino group, allowing for diverse chemical transformations including nucleophilic substitutions and coupling reactions. Its stability under various reaction conditions makes it a preferred choice for multi-step synthesis routes.
- Pharmaceutical Intermediate: Used in the development of kinase inhibitors and receptor modulators.
- Agrochemical Synthesis: Serves as a key building block for novel pesticides and herbicides.
- Material Science: Applied in the creation of organic electronic materials and polymers.
- Research and Development: Essential reagent for academic and industrial laboratory studies.
Quality Assurance and Packaging
We understand the importance of reliability in the supply chain. Each production lot undergoes comprehensive analysis using HPLC, NMR, and MS to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and compliance. Our standard packaging consists of 25 kg drums, though we offer flexible customization to meet specific logistical requirements. Proper storage in a cool, ventilated environment ensures the long-term stability of the product.
Partner with us for a secure supply of high-quality chemical intermediates. Our team is dedicated to supporting your synthesis projects with timely delivery and technical expertise. We adhere to all safety regulations regarding the handling and transportation of chemical substances to ensure a safe working environment for all stakeholders involved in the supply chain.
