Intermediates

2-Amino-4,5-difluorobenzoic Acid

  • CAS No.83506-93-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Amino-4,5-difluorobenzoic Acid designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

2-Amino-4,5-difluorobenzoic Acid is a specialized fluorinated organic compound that serves as a critical building block in modern medicinal chemistry and agrochemical synthesis. Characterized by the presence of two fluorine atoms on the benzene ring alongside an amino group and a carboxylic acid function, this molecule offers unique reactivity profiles essential for constructing complex pharmaceutical architectures. Our facility produces this intermediate under strict quality control standards to ensure consistency across batches.

The introduction of fluorine into organic molecules is a strategic maneuver in drug design, often enhancing metabolic stability, lipophilicity, and bioavailability. As a key precursor, this difluorobenzoic acid derivative enables chemists to develop novel therapeutic agents with improved performance characteristics. We supply this material to research institutions and manufacturing partners globally, supporting innovation in life sciences.

Key Specifications

Our manufacturing process prioritizes high purity and precise physical properties to meet the demanding requirements of downstream synthesis. Each batch undergoes rigorous analytical testing using high-performance liquid chromatography and other standard methodologies.

ParameterSpecification
Chemical Name2-Amino-4,5-difluorobenzoic Acid
CAS Number83506-93-8
Molecular FormulaC7H5F2NO2
Molecular Weight173.12 g/mol
AppearanceBeige powder
Purity (HPLC)≥99.0%
Melting Point181-185°C
Density1.536 g/cm³

Industrial Applications

This compound is primarily utilized as an intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other targeted therapies. The specific positioning of the fluorine atoms allows for selective functionalization, making it a versatile reagent for organic synthesis.

  • Pharmaceutical Intermediate: Used in the production of active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Serves as a building block for novel pesticides and herbicides.
  • Organic Research: Employed in academic and industrial research for method development.
  • Custom Synthesis: Available for tailored production runs based on specific project requirements.

Quality Assurance and Packaging

We understand that reliability is paramount in the chemical supply chain. Our quality assurance team ensures that every drum meets the specified purity levels before shipment. Documentation including Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) is provided with every order to facilitate regulatory compliance and safe handling.

Standard packaging consists of 25 kg fiber drums, which are designed to protect the product from moisture and physical damage during transit. Custom packaging solutions are available upon request to accommodate specific logistical needs or smaller scale research quantities.

Storage and Handling

To maintain product integrity, 2-Amino-4,5-difluorobenzoic Acid should be stored in a cool, ventilated area away from direct sunlight and sources of ignition. The container must be kept tightly closed when not in use to prevent exposure to moisture. Proper personal protective equipment should be worn during handling to ensure safety in the laboratory or production environment.