2-Amino-4-bromopyridine
- CAS No.84249-14-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Amino-4-bromopyridine (CAS 84249-14-9), a versatile pyridine-based intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
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Product Overview
2-Amino-4-bromopyridine is a high-value heterocyclic building block widely employed in the pharmaceutical and fine chemical industries. With its dual functional groups—an electron-rich amino moiety and a reactive bromine atom at strategic positions on the pyridine ring—it serves as a critical scaffold for cross-coupling reactions, nucleophilic substitutions, and multistep syntheses of complex bioactive molecules.
Specifications
| Molecular Formula | C5H5BrN2 |
|---|---|
| Molecular Weight | 173.01 g/mol |
| CAS Number | 84249-14-9 |
| Appearance | White to yellowish-orange powder |
| Purity (GC) | ≥99.0% |
| Density | 1.844 g/cm³ |
| Boiling Point | 340.7°C |
| Flash Point | 159.9°C |
| Refractive Index | 1.648 |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and specialty ligands for catalysis. Its structural features enable efficient derivatization via Suzuki, Buchwald-Hartwig, and other transition metal-catalyzed transformations, making it indispensable in modern medicinal chemistry workflows.
- Ideal for constructing nitrogen-containing heterocycles in drug discovery pipelines
- Serves as a precursor for kinase inhibitors and CNS-targeted therapeutics
- Compatible with standard handling protocols for halogenated aminopyridines
Stored in a cool, dry, and well-ventilated area, 2-Amino-4-bromopyridine maintains stability under recommended conditions. Packaging is typically 25 kg per drum, with custom options available to meet global regulatory and logistical requirements.
